Klotho ameliorates cyclosporine A-induced nephropathy via PDLIM2/NF-kB p65 signaling pathway.
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DOI: 10.1016/j.bbrc.2017.03.061
Abstract: Klotho, an antiaging protein, can extend the lifespan and modulate cellular responses to inflammation and oxidative stress which can ameliorate chronic kidney diseases (CKD). To investigate the molecular mechanism of Klotho on inflammation in cyclosporine… read more here.
Keywords: pdlim2 p65; pdlim2; expression; induced nephropathy ... See more keywords