Articles with "pdlla" as a keyword



Preparation of PDLLA and PLGA nanoparticles stabilized with PVA and a PVA-SDS mixture: Studies on particle size, degradation and drug release

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Published in 2020 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2020.101907

Abstract: Abstract The use of poly(vinyl alcohol) (PVA) and a PVA-sodium dodecyl sulfate mixture (PVA-SDS) for the colloidal stabilization of poly( dl -lactide) (PDLLA) and poly( dl -lactide-co-glycolide) (PLGA) nanoparticles (NPs) loaded with paclitaxel (PTX) was… read more here.

Keywords: pdlla; pva sds; pva; plga ... See more keywords
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Matrix Metalloproteinase-Responsive Multifunctional Peptide-Linked Amphiphilic Block Copolymers for Intelligent Systemic Anticancer Drug Delivery.

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Published in 2017 at "Bioconjugate chemistry"

DOI: 10.1021/acs.bioconjchem.7b00330

Abstract: The amphiphilic block copolymer anticancer drug nanocarriers clinically used or in the progress of clinical trials frequently suffer from modest final therapeutic efficacy due to a lack of intelligent features. For example, the biodegradable amphiphilic… read more here.

Keywords: pdlla; block; chemistry; amphiphilic block ... See more keywords
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A non-conjugated polyethylenimine copolymer-based unorthodox nanoprobe for bioimaging and related mechanism exploration.

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Published in 2019 at "Biomaterials science"

DOI: 10.1039/c9bm00516a

Abstract: Unconventional non-conjugated photoluminescent polymers have attracted increasing attention in bioimaging application, however their nonclassical photoluminescence mechanisms remain largely unclear. Herein, an amphiphilic copolymer polyethyleneimine-poly(d,l-lactide) (PEI-PDLLA) was synthesized and the obtained PEI-PDLLA copolymer exhibited intrinsic visible… read more here.

Keywords: pei pdlla; pdlla; mechanism; non conjugated ... See more keywords
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Poly(D,L-Lactic Acid) (PDLLA) Biodegradable and Biocompatible Polymer Optical Fiber

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Published in 2019 at "Journal of Lightwave Technology"

DOI: 10.1109/jlt.2019.2895220

Abstract: We demonstrate that commercially available poly(D,L-lactic acid) (PDLLA) is a suitable material for the fabrication of biodegradable optical fibers with a standard heat drawing process. To do so we report on the chemical and optical… read more here.

Keywords: poly lactic; lactic acid; pdlla; polymer ... See more keywords
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Capacitive electrical stimulation of a conducting polymeric thin film induces human mesenchymal stem cell osteogenesis.

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Published in 2022 at "Biointerphases"

DOI: 10.1116/6.0001435

Abstract: Electroactive materials based on conductive polymers are promising options for tissue engineering and regenerative medicine applications. In the present work, the conducting copolymers of poly (3,4-ethylenedioxythiophene) and poly (d, l-lactic acid) (PEDOT-co-PDLLA) with PEDOT:PDLLA molar… read more here.

Keywords: pdlla; capacitive electrical; electrical stimulation; mesenchymal stem ... See more keywords
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Efficient Suppression of Liver Metastasis Cancers by Paclitaxel Loaded Nanoparticles in PDLLA-PEG-PDLLA Thermosensitive Hydrogel Composites.

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Published in 2017 at "Journal of biomedical nanotechnology"

DOI: 10.1166/jbn.2017.2454

Abstract: Breast and colonic carcinomas are two main origins of metastatic liver cancer. Chemotherapy, which introduces various anticancer drugs such as paclitaxel, is an important cure for patients who are not suitable for surgery and transcatheter… read more here.

Keywords: pdlla; hydrogel; liver; peg pdlla ... See more keywords
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Electrostatic interactions between polyglutamic acid and polylysine yields stable polyion complex micelles for deoxypodophyllotoxin delivery

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Published in 2017 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s140573

Abstract: To achieve enhanced physical stability of poly(ethylene glycol)-poly(d,l-lactide) polymeric micelles (PEG-PDLLA PMs), a mixture of methoxy PEG-PDLLA-polyglutamate (mPEG-PDLLA-PLG) and mPEG-PDLLA-poly(l-lysine) (mPEG-PDLLA-PLL) copolymers was applied to self-assembled stable micelles with polyion-stabilized cores. Prior to micelle preparation,… read more here.

Keywords: dpt; pdlla; polyion complex; complex micelles ... See more keywords
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Gold Nanoparticles and [PEDOT-Poly(D,L-Lactic Acid)] Composite: Synthesis, Characterization and Application to H2O2 Sensing

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Published in 2019 at "Journal of the Brazilian Chemical Society"

DOI: 10.21577/0103-5053.20190063

Abstract: Biocompatible electrochemical devices are challenging to develop due to the toxicity of many advanced electrode materials and the difficulty to degrade the discarded material. Few recent advances were made in the synthesis of conducting biodegradable… read more here.

Keywords: pdlla; poly lactic; pedot pdlla; synthesis ... See more keywords
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Vancomycin Containing PDLLA and PLGA/β-TCP Inhibit Biofilm Formation but Do Not Stimulate Osteogenic Transformation of Human Mesenchymal Stem Cells

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Published in 2022 at "Frontiers in Surgery"

DOI: 10.3389/fsurg.2022.885241

Abstract: Aims Chronic osteomyelitis, including implant-related prosthetic joint infection, is extremely difficult to cure. We develop vancomycin containing release systems from poly(d,l-lactide) (PDLLA) and poly(d,l-lactide-co-glycolide) (PLGA) composites with beta-tricalcium phosphate (β-TCP) to treat methicillin-resistant Staphylococcus aureus… read more here.

Keywords: pdlla; tcp; plga tcp; biofilm formation ... See more keywords
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Application of a Bioactive/Bioresorbable Three-Dimensional Porous Uncalcined and Unsintered Hydroxyapatite/Poly-d/l-lactide Composite with Human Mesenchymal Stem Cells for Bone Regeneration in Maxillofacial Surgery: A Pilot Animal Study

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Published in 2019 at "Materials"

DOI: 10.3390/ma12050705

Abstract: A novel three-dimensional (3D) porous uncalcined and unsintered hydroxyapatite/poly-d/l-lactide (3D-HA/PDLLA) composite demonstrated superior biocompatibility, osteoconductivity, biodegradability, and plasticity, thereby enabling complex maxillofacial defect reconstruction. Mesenchymal stem cells (MSCs)—a type of adult stem cell—have a multipotent… read more here.

Keywords: stem; pdlla; study; bone regeneration ... See more keywords