Electrospun gelatin matrices with bioactive pDNA polyplexes.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.01.252
Abstract: Recent advances in electrospinning are yielding intricate scaffolds for use in regenerative medicine. To explore the possibility of creating bioactive scaffolds with functional gene expression systems, electrospun gelatin mats bearing plasmid DNA (pDNA) polyplexes are… read more here.
Keywords: electrospun gelatin; pdna polyplexes; bioactive pdna; matrices bioactive ... See more keywords
Physicochemical stability and transfection efficiency of cationic amphiphilic copolymer/pDNA polyplexes for spinal cord injury repair
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DOI: 10.1038/s41598-017-10982-y
Abstract: Multiple age-related and injury-induced characteristics of the adult central nervous system (CNS) pose barriers to axonal regeneration and functional recovery following injury. In situ gene therapy is a promising approach to address the limited availability… read more here.
Keywords: pdna polyplexes; cationic amphiphilic; amphiphilic copolymer; injury ... See more keywords