Regulation of cohesinâmediated chromosome folding by PDS5 in mammals
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DOI: 10.15252/embr.202254853
Abstract: Cohesin regulates sister chromatid cohesion but also contributes to chromosome folding by promoting the formation of chromatin loops, a process mediated by loop extrusion. Although PDS5 regulates cohesin dynamics on chromatin, the exact function of… read more here.
Keywords: cohesin; pds5a pds5b; chromosome folding; cohesin mediated ... See more keywords
Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5.
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DOI: 10.1534/genetics.119.302256
Abstract: Heterochromatin enriched in histone H3 lysine 9 methylation (H3K9me) and HP1 proteins coats chromosomal domains throughout the eukaryotic genome to regulate gene expression and maintain genome stability. How heterochromatin assembly mechanisms are... The fission yeast… read more here.
Keywords: heterochromatin; cohesin; pds5; heterochromatin assembly ... See more keywords