Two‐Photon Absorption Induced Cancer Immunotherapy Using Covalent Organic Frameworks
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202103056
Abstract: Immune checkpoint blockade therapy is revolutionizing the traditional treatment model of multiple tumor types, but remains ineffective for a large subset of patients. Photodynamic therapy (PDT) has been shown to induce cancer cell death and… read more here.
Keywords: cancer; two photon; pdt; therapy ... See more keywords
Soft X-Ray Stimulated Lanthanide@MOF Nanoprobe for Amplifying Deep Tissue Synergistic Photodynamic and Antitumor Immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101174
Abstract: Combining photodynamic therapy (PDT) and immunotherapy has shown profound impact for synergistic treatment of malignant tumors. However, the shallow penetration depth of the traditional visible light activated PDT, immunosuppressive tumor microenvironment (TME), and poor immunogenicity… read more here.
Keywords: deep tissue; immunotherapy; ray; pdt ... See more keywords
Engineering H2O2 and O2 Self‐Supplying Nanoreactor to Conduct Synergistic Chemiexcited Photodynamic and Calcium‐Overloaded Therapy in Orthotopic Hepatic Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201613
Abstract: Photodynamic therapy (PDT) is traditionally ineffective for deeply embedded tumors due to the poor penetration depth of the excitation light. Chemiluminescence resonance energy transfer (CRET) has emerged as a promising mode of PDT without external… read more here.
Keywords: calcium; overloaded therapy; therapy orthotopic; therapy ... See more keywords
Switchable ROS Scavenger/Generator for MRI‐Guided Anti‐Inflammation and Anti‐Tumor Therapy with Enhanced Therapeutic Efficacy and Reduced Side Effects
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202043
Abstract: Photosensitizer in photodynamic therapy (PDT) accumulates in both tumor and adjacent normal tissue due to low selective biodistribution, results in undesirable side effect with limited clinic application. Herein, an intelligent nanoplatform is reported that selectively… read more here.
Keywords: scavenger generator; ros scavenger; normal tissue; tumor ... See more keywords
Polypyridyl Ruthenium(II) Complexes with Red‐Shifted Absorption: New Promises in Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100102
Abstract: In the field of cancer photodynamic therapy (PDT) research, development of metal‐based PDT drugs that can be used under red light exposure is the “holy grail” to achieve. This highlight highlighted few current literatures on… read more here.
Keywords: pdt; photodynamic therapy; shifted absorption; red shifted ... See more keywords
Correlation of intracellular oxygen and cell metabolism by simultaneous PLIM of phosphorescent TLD1433 and FLIM of NAD(P)H.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201800085
Abstract: During photodynamic therapy (PDT), disruption of cell respiration and metabolic changes could be one of the first events. Photophysical characteristics of the photosensitizer (PS) and its specific redox potential define consumption of molecular oxygen followed… read more here.
Keywords: flim; oxygen; metabolism; pdt ... See more keywords
Positive effects of low‐dose photodynamic therapy with aminolevulinic acid or its methyl ester in skin rejuvenation and wound healing: An update
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200293
Abstract: In dermatology, photodynamic therapy (PDT) is widely used in skin tumors, infections, etc., because of the killing effect triggered by toxic reactive oxygen species (ROS). However, the ROS concentration is determined by various photosensitizer concentrations… read more here.
Keywords: wound healing; dermatology; positive effects; photodynamic therapy ... See more keywords
Reversal of the Migratory and Invasive Phenotype of Ras‐Transfected Mammary Cells by Photodynamic Therapy Treatment
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25657
Abstract: Photodynamic therapy (PDT) is a non‐thermal technique for inducing tumor damage following administration of a light‐activated photosensitizing drug (PS). In a previous work we found that PDT induces cytoskeleton changes in HB4a‐Ras cells (human mammary… read more here.
Keywords: migratory invasive; hb4a ras; pdt treated; pdt ... See more keywords
Choroidal remodeling after photodynamic therapy for polypoidal choroidal vasculopathy
Sign Up to like & getrecommendations! Published in 2018 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.22998
Abstract: We read with interest the article by Chen et al. [1] describing choroidal remodeling in eyes with polypoidal choroidal vasculopathy (PCV) following treatment with verteporfin photodynamic therapy (PDT). Using spectraldomain optical coherence tomography (OCT), the… read more here.
Keywords: choroidal; treatment; pdt; choroidal remodeling ... See more keywords
The Immunogenetic Aspects of Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-92616-8_18
Abstract: Photodynamic therapy (PDT) has become the first-line treatment of actinic keratosis, superficial basal cell carcinoma, and squamous cell carcinoma in situ (Bowen's disease) in dermatology. The off-label use of PDT has also escalated in recent… read more here.
Keywords: pdt; photodynamic therapy; dermatology; immunogenetic aspects ... See more keywords
One-year efficacy of “rescue photodynamic therapy” for patients with typical age-related macular degeneration, polypoidal choroidal vasculopathy, and pachychoroid neovasculopathy refractory to anti-vascular endothelial growth factor therapy
Sign Up to like & getrecommendations! Published in 2022 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-022-05553-5
Abstract: Purpose This study aimed to evaluate the one-year outcomes of photodynamic therapy (PDT) as a rescue treatment for age-related macular degeneration (AMD) refractory to anti-vascular endothelial growth factor (VEGF) therapy. Methods Patients with AMD refractory… read more here.
Keywords: age; refractory anti; pdt; therapy ... See more keywords