Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF‐&kgr;B activity
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.07.038
Abstract: Aims: Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely used and effective anti‐inflammatories despite the well‐known side effects such as gastrointestinal damage, acute kidney injury (AKI), and cardiovascular dysfunctions. Diclofenac is among the most prescribed NSAIDs due… read more here.
Keywords: pdtc; diclofenac induced; acute kidney; damage ... See more keywords
FNA diagnosis of poorly differentiated thyroid carcinoma. A review of the recent literature
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DOI: 10.1111/cyt.12497
Abstract: Poorly differentiated thyroid carcinoma (PDTC) is a follicular cell‐derived tumour that was recognised as a distinct entity by the World Health Organisation in 2004. The natural history and pathological features of PDTC are reported to… read more here.
Keywords: diagnosis pdtc; poorly differentiated; diagnosis; pdtc ... See more keywords
Developing membrane-derived nanocarriers for ex vivo therapy of homologous breast cancer cells.
Sign Up to like & getrecommendations! Published in 2021 at "Nanomedicine"
DOI: 10.2217/nnm-2021-0153
Abstract: Aim: The primary aim of this study was to develop biomimetic nanocarriers for specific homologous targeting of the anticancer drugs ammonium pyrrolidine dithiocarbamate (PDTC) and doxorubicin. Methods: Membranous nanovesicles were synthesized from a breast cancer cell line… read more here.
Keywords: pdtc; cell; membrane derived; breast cancer ... See more keywords
FGF-Receptors and PD-L1 in Anaplastic and Poorly Differentiated Thyroid Cancer: Evaluation of the Preclinical Rationale
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DOI: 10.3389/fendo.2021.712107
Abstract: Background Treatment options for poorly differentiated (PDTC) and anaplastic (ATC) thyroid carcinoma are unsatisfactory and prognosis is generally poor. Lenvatinib (LEN), a multi-tyrosine kinase inhibitor targeting fibroblast growth factor receptors (FGFR) 1-4 is approved for… read more here.
Keywords: poorly differentiated; pdtc; atc pdtc; fgf receptors ... See more keywords
Role of Δ133p53 isoform in NF-κB inhibitor PDTC-mediated growth inhibition of MKN45 gastric cancer cells
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DOI: 10.3748/wjg.v23.i15.2716
Abstract: AIM To investigate the role of Δ133p53 isoform in nuclear factor-κB (NF-κB) inhibitor pyrrolidine dithiocarbamate (PDTC)-mediated growth inhibition of MKN45 gastric cancer cells. METHODS The growth rate of MKN45 cells after treatment with different concentrations… read more here.
Keywords: gastric cancer; pdtc; treatment; p53 ... See more keywords
[Effect of pyrrolidine dithiocarbamate on oxidative stress and mitochondrial function of lung tissue in mice with acute lung injury].
Sign Up to like & getrecommendations! Published in 2018 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.issn.2095-4352.2018.05.007
Abstract: OBJECTIVE To investigate the effects of pyrrolidine dithiocarbamate (PDTC) on oxidative stress and mitochondrial function of lung tissue in mice with acute lung injury (ALI) induced by lipopolysaccharide (LPS). METHODS Forty female Balb/c mice were… read more here.
Keywords: pdtc; group; lung tissue; mice ... See more keywords