Personalized medicine modality based on patient-derived xenografts from a malignant transformed GCTB harboring H3F3A G34W mutation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Orthopaedic Translation"
DOI: 10.1016/j.jot.2021.04.004
Abstract: Background The function of H3F3A G43W mutation, which has been observed in almost all GCTB, remains poorly characterized. Breakthrough in malignant GCTB has been trapped by the lack of clinical available drugs, limited canonical patient… read more here.
Keywords: medicine; malignant gctb; pdx model; h3f3a ... See more keywords
Changes in the Urinary Proteome in a Patient-Derived Xenograft (PDX) Nude Mouse Model of Colorectal Tumor
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DOI: 10.1038/s41598-019-41361-4
Abstract: In this report, the urinary proteome from a patient-derived xenograft (PDX) model was examined at the peptide level to study the origins of urinary proteins in tumor-bearing nude mice. Urine was collected from PDX mice… read more here.
Keywords: pdx model; proteome patient; urinary proteome; model ... See more keywords
Genomic profile of metastatic breast cancer patient-derived xenografts established using percutaneous biopsy
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DOI: 10.1186/s12967-020-02607-2
Abstract: Background Metastatic breast cancer (mBC) is a complex and life-threatening disease and although it is difficult to cure, patients can benefit from sequential anticancer treatment, including endocrine therapy, targeted therapy and cytotoxic chemotherapy. The patient-derived… read more here.
Keywords: biopsy; pdx model; breast cancer; metastatic breast ... See more keywords
Preparation and application of patient-derived xenograft mice model of colorectal cancer
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.67445.14780
Abstract: Objective(s): Patient-derived xenograft (PDX) model becomes a more and more important tool for tumor research. This study aimed to establish a colorectal cancer PDX model and verify its applicability. Materials and Methods: Fresh human colorectal… read more here.
Keywords: pdx model; tumor; colorectal cancer; model ... See more keywords
Application status and future prospects of the PDX model in lung cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1098581
Abstract: Lung cancer is one of the most prevalent, fatal, and highly heterogeneous diseases that, seriously threaten human health. Lung cancer is primarily caused by the aberrant expression of multiple genes in the cells. Lung cancer… read more here.
Keywords: lung cancer; pdx model; cancer; biology ... See more keywords