Thiamine‐dependent regulation of mammalian brain pyridoxal kinase in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15576
Abstract: Vitamins B1 (thiamine) and B6 (pyridox (al/ine/amine)) are crucial for central nervous system (CNS) function and neurogenesis due to the coenzyme action of their phosphorylated derivatives in the brain metabolism of glucose and neurotransmitters. Here,… read more here.
Keywords: vitro vivo; thiamine; pyridoxal kinase; pdxk ... See more keywords
The Crystal Structure of the Plasmodium falciparum PdxK Provides an Experimental Model for Pro-Drug Activation
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DOI: 10.3390/cryst9100534
Abstract: Pyridoxine/pyridoxal kinase (PdxK), belongs to the ribokinase family and is involved in the vitamin B6 salvage pathway by phosphorylating 5-pyridoxal (PL) into an active form. In the human malaria parasite, Plasmodium falciparum, PfPdxK functions to… read more here.
Keywords: crystal structure; pdxk; model; plasmodium falciparum ... See more keywords