Pyroglutamate–amyloid-&bgr; peptide expression in Drosophila leads to caspase-dependent and endoplasmic reticulum stress–related progressive neurodegeneration
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DOI: 10.1093/hmg/ddx346
Abstract: Alzheimer's disease (AD) is the most common neurodegenerative disorder among the elderly. During the progression of AD, massive neuronal degeneration occurs in the late stage of the disease; however, the molecular mechanisms responsible for this… read more here.
Keywords: pe3; caspase dependent; neurodegeneration; expression ... See more keywords