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NLRP2 Is Overexpressed in Spinal Astrocytes at the Peak of Mechanical Pain Sensitivity during Complete Freund Adjuvant-Induced Persistent Pain

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222111408

Abstract: Our earlier findings revealed that interleukin-1 receptor type-1 (IL-1R1) was overexpressed in spinal neurons, and IL-1R1-deficient mice showed significant attenuation of thermal and mechanical allodynia during the course of the Complete Freund adjuvant (CFA)-induced persistent… read more here.

Keywords: persistent pain; overexpressed spinal; complete freund; freund adjuvant ... See more keywords