Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family
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DOI: 10.1126/scisignal.abj3554
Abstract: The pseudokinase scaffolds PEAK1 and PEAK2 are implicated in cancer cell migration and metastasis. We characterized the regulation and role of the third family member PEAK3 in cell signaling. Similar to PEAK1 and PEAK2, PEAK3… read more here.
Keywords: peak3; pseudokinase; peak1 peak2; cell ... See more keywords
Piquing our interest: Insights into the role of PEAK3 in signaling and disease
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abm9396
Abstract: Pseudokinases are critical signaling hubs that are increasingly appreciated as important disease targets. In this issue of Science Signaling, Hou et al. bring new insights into the signaling mechanisms of the pseudokinase PEAK3 by characterizing… read more here.
Keywords: disease; interest insights; insights role; peak3 ... See more keywords