Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study
Sign Up to like & getrecommendations! Published in 2019 at "The Lancet"
DOI: 10.1016/s0140-6736(19)31793-3
Abstract: BACKGROUND Dietary avoidance is recommended for peanut allergies. We evaluated the sustained effects of peanut allergy oral immunotherapy (OIT) in a randomised long-term study in adults and children. METHODS In this randomised, double-blind, placebo-controlled, phase… read more here.
Keywords: placebo; peanut; study; peanut allergy ... See more keywords
Evaluation of the epidemiology of peanut allergy in the United Kingdom
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2020.1693264
Abstract: ABSTRACT Aims: To describe the epidemiology of peanut allergy (PA) in the UK over the last three decades. Methods: PA patients were identified from the Clinical Practice Research Datalink between 1987 and 2015. Incidence and… read more here.
Keywords: epidemiology peanut; per 100; peanut allergy; 100 000 ... See more keywords
Peanut (Arachis hypogaea) allergen powder-dnfp for the mitigation of allergic reactions to peanuts in children and adolescents
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2023.2159812
Abstract: ABSTRACT Introduction Peanut allergy can result in severe, sometimes fatal hypersensitivity reactions that place a considerable burden on the lives of patients. This article reviews the first approved immunotherapy for the mitigation of allergic reactions… read more here.
Keywords: peanut allergy; peanut arachis; peanut; allergen ... See more keywords
Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success.
Sign Up to like & getrecommendations! Published in 2023 at "Expert review of clinical immunology"
DOI: 10.1080/1744666x.2023.2209318
Abstract: INTRODUCTION Peanut oral immunotherapy (pOIT) is the only FDA-approved treatment for food allergy and its adoption amongst allergist immunologists and their patients is growing. pOIT is the subject of numerous clinical trials, however, the focus… read more here.
Keywords: best practices; allergy risk; oral immunotherapy; peanut allergy ... See more keywords
Current insights: a systemic review of therapeutic options for peanut allergy
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000824
Abstract: Purpose of review With increasing prevalence of peanut allergy (PA) globally and the greater risk of potential reactions occurring due to the leading role of nuts in food products, PA has become a significant public… read more here.
Keywords: systemic review; peanut allergy; review; current insights ... See more keywords
Allergenicity of peanut allergens and its dependence on the structure.
Sign Up to like & getrecommendations! Published in 2023 at "Comprehensive reviews in food science and food safety"
DOI: 10.1111/1541-4337.13101
Abstract: Food allergies are a global food safety problem. Peanut allergies are common due, in part, to their popular utilization in the food industry. Peanut allergy is typically an immunoglobulin E-mediated reaction, and peanuts contain 17 allergens… read more here.
Keywords: structure; peanut allergens; peanut allergy; food ... See more keywords
Study raises hopes of minimising risk of life threatening peanut allergy reactions
Sign Up to like & getrecommendations! Published in 2018 at "British Medical Journal"
DOI: 10.1136/bmj.k4879
Abstract: Children and young people with peanut allergy exposed to gradually increasing doses of peanut allergen were then able to ingest far higher doses of peanut protein, a randomised trial has found. The findings, published in… read more here.
Keywords: raises hopes; minimising risk; peanut allergy; hopes minimising ... See more keywords
Peanut Allergy in Spanish Children: Comparative Profile of Peanut Allergy versus Tolerance
Sign Up to like & getrecommendations! Published in 2019 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000495579
Abstract: Background: Peanut storage proteins (Ara h 1, Ara h 2, and Ara h 3) have been described as the major peanut allergens in children, although not all peanut-sensitized individuals have clinical reactivity after exposure. Objectives:… read more here.
Keywords: peanut storage; ara ara; peanut allergic; peanut ... See more keywords
Targeted DNA methylation profiling reveals epigenetic signatures in peanut allergy
Sign Up to like & getrecommendations! Published in 2021 at "JCI Insight"
DOI: 10.1172/jci.insight.143058
Abstract: DNA methylation (DNAm) has been shown to play a role in mediating food allergy; however, the mechanism by which it does so is poorly understood. In this study, we used targeted next-generation bisulfite sequencing to… read more here.
Keywords: methylation; peanut allergy; dna methylation; targeted dna ... See more keywords
Another Person’s Peril: Peanut Allergy, Risk Perceptions, and Responsible Sociality
Sign Up to like & getrecommendations! Published in 2022 at "American Sociological Review"
DOI: 10.1177/00031224211067773
Abstract: This article examines perceptions of health risk when some individuals within a shared space are in heightened danger but anyone, including unaffected others, can be a vector of risk. Using the case of peanut allergy… read more here.
Keywords: responsible sociality; risk; peanut allergy;
A study to assess current approaches of allergists in European countries diagnosing and managing children and adolescents with peanut allergy
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0241648
Abstract: Rationale Food allergy is documented to result in considerable morbidity, negative impact on quality of life, and substantial medical care costs. Although anecdotal data suggest widely varying practices in the diagnosis and management of food… read more here.
Keywords: assess current; study assess; diagnosis; allergists reported ... See more keywords