Novel subgroups in acute respiratory failure based on the trajectories of three endotheliopathy biomarkers: A cohort study.
Sign Up to like & getrecommendations! Published in 2023 at "Acta anaesthesiologica Scandinavica"
DOI: 10.1111/aas.14246
Abstract: Baseline levels of endotheliopathy are associated with worse respiratory outcomes and mortality in undifferentiated acute respiratory failure (ARF), but knowledge is lacking on the development of endotheliopathy over time in ARF. We, therefore, aimed to… read more here.
Keywords: baseline; pecam; acute respiratory; respiratory failure ... See more keywords
PECAM‐1 modulates liver damage induced by synergistic effects of TNF‐α and irradiation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14224
Abstract: The mechanisms of radiation‐induced liver damage are poorly understood. We investigated if tumour necrosis factor (TNF)‐α acts synergistically with irradiation, and how its activity is influenced by platelet endothelial cell adhesion molecule‐1 (PECAM‐1). We studied… read more here.
Keywords: irradiation; hepatic damage; liver damage; pecam ... See more keywords
PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00711
Abstract: Breakdown of the blood-brain barrier (BBB) and increased immune cell trafficking into the central nervous system (CNS) are hallmarks of the pathogenesis of multiple sclerosis (MS). Platelet endothelial cell adhesion molecule-1 (PECAM-1; CD31) is expressed… read more here.
Keywords: blood brain; bbb; pecam; brain barrier ... See more keywords
Prognostic Implication of the Expression Level of PECAM-1 in Non-small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.587744
Abstract: Background: Lung cancer is a malignant disease that threatens human health. Hence, it is crucial to identify effective prognostic factors and treatment targets. Single-cell RNA sequencing can quantify the expression profiles of transcripts in individual… read more here.
Keywords: pecam; expression; lung cancer; cancer ... See more keywords
Development of A New Mouse Model for Intrahepatic Cholangiocellular Carcinoma: Accelerating Functions of Pecam-1
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11081045
Abstract: Due to the lack of suitable in-vivo models, the etiology of intrahepatic cholangiocellular carcinoma (ICC) is poorly understood. We previously showed the involvement of platelet endothelial cell adhesion molecule-1 (Pecam-1/CD31) in acute liver damage. Here,… read more here.
Keywords: cholangiocellular carcinoma; pecam; mice; mouse model ... See more keywords
PECAM-1 overexpression signifies aggressive biologic behavior of oral lichen planus – A pilot study
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Dental Research"
DOI: 10.4103/ijdr.ijdr_653_18
Abstract: Context: The etiopathogenesis of oral lichen planus (OLP) is still debatable. According to literature, many studies have illustrated OLP as a T-cell-mediated chronic autoimmune disease. Currently, there is increased evidence of chronic inflammation in OLP… read more here.
Keywords: lichen planus; pecam; study; oral lichen ... See more keywords