Highly efficient bioreduction of 2-hydroxyacetophenone to (S)- and (R)-1-phenyl-1,2-ethanediol by two substrate tolerance carbonyl reductases with cofactor regeneration.
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DOI: 10.1016/j.jbiotec.2016.12.016
Abstract: Optically pure 1-phenyl-1,2-ethanediol is a very important chiral building block and intermediate in fine chemical and pharmaceutical industries. Reduction of 2-hydroxyacetophenone provides a straightforward approach to access these important compounds. In this study, two enantiocomplementary… read more here.
Keywords: phenyl ethanediol; carbonyl reductases; cofactor regeneration; ped ped ... See more keywords