Clinical outcomes and prognostic factors in children with B-cell lymphoblastic lymphoma (LBL) treated according to on modified BFM-90 protocol: Experience from a Tertiary cancer care center in India.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric hematology and oncology"
DOI: 10.1080/08880018.2021.2005725
Abstract: Pediatric B-cell lymphoblastic lymphoma (LBL) is a rare entity, and appropriate treatment for pediatric B-cell LBL is not well defined. While intensive ALL type regimens achieve long term survival of 90% across Western co-operative group… read more here.
Keywords: protocol; cell lymphoblastic; bfm protocol; pediatric cell ... See more keywords
Rare TCF3 variants associated with pediatric B cell acute lymphoblastic leukemia.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric hematology and oncology"
DOI: 10.1080/08880018.2023.2201302
Abstract: Germline genetic variants influence development of pediatric B cell acute lymphoblastic leukemia (B-ALL). Genome-wide association studies (GWAS) have identified several pediatric B-ALL susceptibility loci. IKZF1 and PAX5, transcription factors involved in B cell development, have… read more here.
Keywords: cell; pediatric cell; development; tcf3 ... See more keywords
Perspectives of Fc engineered antibodies in CD19 targeting immunotherapies in pediatric B-cell precursor acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Oncoimmunology"
DOI: 10.1080/2162402x.2018.1448331
Abstract: ABSTRACT CD19 immunotherapies based on T cells opened new avenues in the treatment of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However, Fc engineered CD19 antibodies may also bear great potential. In light of recent… read more here.
Keywords: precursor acute; lymphoblastic leukemia; cell precursor; acute lymphoblastic ... See more keywords
Abstract 3551: Single-cell characterization of pediatric T-cell acute lymphoblastic leukemia transcriptomes
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3551
Abstract: Pediatric T-cell acute lymphoblastic leukemia (T-ALL) is a rare cancer with a diverse set of causative genomic abnormalities. The variety and limited characterization of genomic mechanisms underlying this disease presents a unique challenge for the… read more here.
Keywords: cell; pediatric cell; single cell; acute lymphoblastic ... See more keywords
Cuplike nuclear morphology in pediatric B-cell acute lymphoblastic leukemia.
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-05-848788
Abstract: ![Figure][1] A 7-year-old previously healthy girl presented with fever, fatigue, and weight loss for 1 month. Laboratory test revealed normocytic anemia (hemoglobin, 7.1 g/dL), neutropenia (0.17 × 109/L), and 30% small- to medium-sized blasts with… read more here.
Keywords: cell acute; cuplike nuclear; cuplike; morphology pediatric ... See more keywords
Clinical Impacts of Copy Number Variations in B-cell Differentiation and Cell Cycle Control Genes in Pediatric B-cell Acute Lymphoblastic Leukemia: a Single Centre Experience
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DOI: 10.2478/raon-2021-0050
Abstract: Abstract Background IKZF1 gene deletions have been identified as a poor prognostic factor in pediatric B-cell acute lymphoblastic leukemia (B-ALL), especially in the presence of co-occurring deletions (IKZF1plus profile). This study aimed to determine the… read more here.
Keywords: cell acute; number variations; cell; pediatric cell ... See more keywords
Case Report: Whole genome sequencing identifies CCDC88C as a novel JAK2 fusion partner in pediatric T-cell acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.1082986
Abstract: In the present report, we applied whole genome sequencing (WGS) to genetically characterize a case of pediatric T-cell acute lymphoblastic leukemia (ALL) refractory to standard therapy. WGS identified a novel JAK2 fusion, with CCDC88C as… read more here.
Keywords: fusion; genome sequencing; pediatric cell; partner ... See more keywords