BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
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DOI: 10.1158/2159-8290.cd-21-1491
Abstract: The BAF complex, in particular ATPase subunit SMARCA4/BRG1, is critical for maintaining pediatric H3K27M-glioma cells in an oncogenic progenitor state, and pharmacologic inhibition is a potential therapeutic avenue for these highly aggressive tumors. read more here.
Keywords: h3k27m glioma; pediatric h3k27m; baf complex;