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   Articles with "pediatric inspired" as a keyword



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Comparison of intensive, pediatric-inspired therapy with non-intensive therapy in older adults aged 55-65 years with Philadelphia chromosome-negative acute lymphoblastic leukemia.

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recommendations! Published in 2018 at "Leukemia research"

DOI: 10.1016/j.leukres.2018.03.010

Abstract: BACKGROUND AND OBJECTIVE The standardization of treatment of older adults with Philadelphia chromosome negative (Ph-) acute lymphoblastic leukemia (ALL) is challenging, especially in the age range of 55-65 years. This study aimed to compare intensive,… read more here.

Keywords: pediatric inspired; chromosome negative; negative acute; philadelphia chromosome ... See more keywords

Combination of Dasatinib and Pediatric-Inspired Regimens in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Single-Center Prospective Study

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-126480

Abstract: Background: Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) is a rare subtype of acute lymphoblastic leukemia with a poor long-term prognosis. Recent studies suggested that the addition of tyrosine kinase inhibitor (TKI) to the traditional… read more here.

Keywords: pediatric inspired; newly diagnosed; lymphoblastic leukemia; study ... See more keywords
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Pediatric-inspired chemotherapy incorporating pegaspargase is safe and results in high rates of minimal residual disease negativity in adults up to the age of 60 years with Philadelphia chromosome-negative acute lymphoblastic leukemia

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recommendations! Published in 2020 at "Haematologica"

DOI: 10.3324/haematol.2020.251686

Abstract: Administration of pediatric-inspired chemotherapy to adults up to age 60 with acute lymphoblastic leukemia (ALL) is challenging in part due to toxicities of asparaginase as well as myelosuppression. We conducted a multi-center phase II clinical… read more here.

Keywords: chemotherapy; adults age; pediatric inspired; acute lymphoblastic ... See more keywords