Flow Cytometry in Pediatric Malignancies
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DOI: 10.1007/s13312-018-1229-0
Abstract: The utility of flow cytometry as a useful diagnostic modality for the assessment of hematopoietic neoplasms has been established beyond doubt. In fact, it is now an integral part of the diagnosis and classification of… read more here.
Keywords: pediatric malignancies; cytometry; cytometry pediatric; flow cytometry ... See more keywords
Limitations and opportunities for immune checkpoint inhibitors in pediatric malignancies.
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DOI: 10.1016/j.ctrv.2017.05.006
Abstract: Immune checkpoint inhibitors (ICI) have shown great promise in a wide spectrum of adult solid and hematological malignancies, achieving objective tumor responses and prolonging survival. However, there is limited clinical success amongst pediatric patients. In… read more here.
Keywords: immune checkpoint; pediatric malignancies; checkpoint inhibitors; opportunities immune ... See more keywords
Targeting the DNA damage response in pediatric malignancies
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DOI: 10.1080/14737140.2022.2124970
Abstract: ABSTRACT Introduction High levels of DNA damage and mutations in DNA damage response genes create a high reliance on DNA damage repair in various tumors. This creates a vulnerability for new cancer therapies. Although there… read more here.
Keywords: pediatric malignancies; dna damage; damage response; damage ... See more keywords
Landscape of Germline and Somatic Mitochondrial DNA Mutations in Pediatric Malignancies.
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DOI: 10.1158/0008-5472.can-18-2220
Abstract: Little is known about the spectrum of mitochondrial DNA (mtDNA) mutations across pediatric malignancies. In this study, we analyzed matched tumor and normal whole genome sequencing data from 616 pediatric patients with hematopoietic malignancies, solid… read more here.
Keywords: landscape germline; pediatric malignancies; mtdna; mitochondrial dna ... See more keywords
Demographic profile of pediatric malignancies in Himachal Pradesh
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DOI: 10.4103/ijmpo.ijmpo_186_16
Abstract: Context: Pediatric malignancy is on the rise worldwide, and it is imperative to know the profile of pediatric malignancy in different geographical areas so as to formulate effective strategy to its control. As there are… read more here.
Keywords: pediatric malignancies; demographic profile; himachal pradesh; malignancy ... See more keywords