Considering the Future of Pediatric Multiple Sclerosis Trials After the CONNECT Open-Label Randomized Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.30451
Abstract: The approach to treatment of relapsing-remitting multiple sclerosis (RRMS) is rapidly evolving, with more than 15 disease-modifying therapies (DMTs) currently licensed for adults. Current treatment algorithms in children with multiple sclerosis (MS) remain heavily reliant… read more here.
Keywords: sclerosis; future pediatric; considering future; trial ... See more keywords
Comparing Natural History of Early and Late Onset Pediatric Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26322
Abstract: This study was undertaken to describe and compare disease course and prognosis of early (ie, disease onset before age 11 years) and late (ie, disease onset after age 11 years) onset pediatric multiple sclerosis. read more here.
Keywords: natural history; onset pediatric; pediatric multiple; multiple sclerosis ... See more keywords
Imaging in Pediatric Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-020-00929-8
Abstract: Pediatric-onset multiple sclerosis (POMS) is defined by a first multiple sclerosis (MS) attack occurring before 18 years old and is diagnosed by demonstration of dissemination in time (DIT) and space (DIS). Although guidelines evolved over the years,… read more here.
Keywords: sclerosis; pediatric multiple; diagnosis; imaging pediatric ... See more keywords
Two-year follow-up during fingolimod treatment in a pediatric multiple sclerosis patient still active on first-line treatment
Sign Up to like & getrecommendations! Published in 2021 at "Neurological Sciences"
DOI: 10.1007/s10072-021-05058-9
Abstract: Treatment of pediatric multiple sclerosis (MS) has been increasingly debated in the last few years due to limited knowledge of treatment strategies and therapeutic options. When MS develops at a young age, it usually has… read more here.
Keywords: pediatric multiple; treatment pediatric; treatment; multiple sclerosis ... See more keywords
Pediatric Multiple Sclerosis: an Update
Sign Up to like & getrecommendations! Published in 2018 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-018-0886-7
Abstract: Purpose of ReviewDiagnostic criteria for pediatric-onset multiple sclerosis (POMS) and related demyelinating disorders have been updated, neuroimaging studies have revealed new insights, biological assays identify patients with specific antibodies that influence both diagnosis and treatment,… read more here.
Keywords: sclerosis; pediatric multiple; time; multiple sclerosis ... See more keywords
The Gut Microbiota and Pediatric Multiple Sclerosis: Recent Findings
Sign Up to like & getrecommendations! Published in 2017 at "Neurotherapeutics"
DOI: 10.1007/s13311-017-0574-3
Abstract: Pediatric multiple sclerosis (MS) is a chronic, life-long neurological condition associated with inflammation and degeneration in the brain and spinal cord. Fortunately, < 5% of people with MS have their onset in childhood years. However,… read more here.
Keywords: multiple sclerosis; gut microbiota; pediatric multiple;
Cognitive functions in pediatric multiple sclerosis: 2-years follow-up
Sign Up to like & getrecommendations! Published in 2020 at "Neurological Research"
DOI: 10.1080/01616412.2019.1710417
Abstract: ABSTRACT Objective: To assess the neuropsychological status of pediatric multiple sclerosis (MS) patients and its relationship with clinical variables in a longitudinal study. Methods: Patients with MS (n = 46) and age- and gender-matched healthy… read more here.
Keywords: verbal reasoning; pediatric multiple; years follow; multiple sclerosis ... See more keywords
Pediatric multiple sclerosis: developments in timely diagnosis and prognostication.
Sign Up to like & getrecommendations! Published in 2022 at "Expert review of neurotherapeutics"
DOI: 10.1080/14737175.2022.2064743
Abstract: INTRODUCTION Pediatric-onset (PO) multiple sclerosis (MS) accounts for about 2-10% of the total MS cases. Recently, a greater attention has been given to POMS, with substantial improvements in the understanding of its pathophysiology, in the… read more here.
Keywords: diagnosis; pediatric multiple; sclerosis; multiple sclerosis ... See more keywords
Refining the Pediatric Multiple Organ Dysfunction Syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatrics"
DOI: 10.1542/peds.2021-052888c
Abstract: Since its introduction into the medical literature in the 1970s, the term multiple organ dysfunction syndrome (or some variant) has been applied broadly to any patient with >1 concurrent organ dysfunction. However, the epidemiology, mechanisms,… read more here.
Keywords: dysfunction syndrome; multiple organ; organ dysfunction; dysfunction ... See more keywords
Incidence of Pediatric Multiple Sclerosis in Iran within 2000-2019
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Child Neurology"
DOI: 10.22037/ijcn.v16i1.35572
Abstract: Objectives Due to a lack of data on pediatric multiple sclerosis (MS) epidemiology in Iran, this study aimed to determine the incidence rate of pediatric MS in Iran. Materials & Methods All the data of… read more here.
Keywords: 2000 2019; iran; incidence; within 2000 ... See more keywords
The State of the Art of Pediatric Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098251
Abstract: Multiple sclerosis (MS) represents a chronic immune-mediated neurodegenerative disease of the central nervous system that generally debuts around the age of 20–30 years. Still, in recent years, MS has been increasingly recognized among the pediatric… read more here.
Keywords: etiology; state art; pediatric multiple; multiple sclerosis ... See more keywords