Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.0595
Abstract: Key Points Question What is the risk of cancer among patients with pediatric-onset inflammatory bowel disease (IBD)? Findings This meta-analysis of 5 unselected, population-based cohort studies comprising 19 812 individuals found a 2.4-fold increased rate of… read more here.
Keywords: pediatric onset; onset inflammatory; cancer among; patients pediatric ... See more keywords
Effect of Dimethyl Fumarate vs Interferon β-1a in Patients With Pediatric-Onset Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.30439
Abstract: This randomized clinical trial investigates the efficacy and safety of dimethyl fumarate vs interferon β-1a for treatment of pediatric-onset multiple sclerosis. read more here.
Keywords: onset multiple; pediatric onset; multiple sclerosis; dimethyl fumarate ... See more keywords
miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.786
Abstract: Onset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped‐MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small noncoding… read more here.
Keywords: contributions pediatric; mirna contributions; multiple sclerosis; onset multiple ... See more keywords
Microvascular decompression for pediatric onset trigeminal neuralgia: patterns and variation
Sign Up to like & getrecommendations! Published in 2022 at "Child's Nervous System"
DOI: 10.1007/s00381-021-05432-0
Abstract: Pediatric trigeminal neuralgia has been rarely reported in the literature, which were only 28 cases. Although microvascular decompression (MVD) has been widely accepted as effective therapy for trigeminal neuralgia, the etiology and surgical treatment of… read more here.
Keywords: trigeminal neuralgia; neuralgia; microvascular decompression; pediatric onset ... See more keywords
Treatment of pediatric-onset lupus nephritis: a proposal of optimal therapy
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-017-1381-1
Abstract: Lupus nephritis (LN) is one of the major clinical manifestations of systemic lupus erythematosus (SLE) which occurs frequently in the early stages of pediatric-onset cases. Since SLE is a chronic disease associated with frequent disease… read more here.
Keywords: therapy; lupus nephritis; treatment; pediatric onset ... See more keywords
Two Sides of the Same Coin: Pediatric-Onset and Adult-Onset Common Variable Immune Deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-017-0415-5
Abstract: PurposeCommon variable immunodeficiency (CVID) is a complex, heterogeneous immunodeficiency characterized by hypogammaglobulinemia, recurrent infections, and poor antibody response to vaccination. While antibiotics and immunoglobulin prophylaxis have significantly reduced infectious complications, non-infectious complications of autoimmunity, inflammatory… read more here.
Keywords: cvid patients; adult onset; adult; pediatric onset ... See more keywords
Newer Treatment Approaches in Pediatric-Onset Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Current Treatment Options in Neurology"
DOI: 10.1007/s11940-019-0592-z
Abstract: With the recognition that pediatric-onset multiple sclerosis (POMS) is characterized by more prominent disease activity, earlier age at onset of disability milestones, and more prominent cognitive impairment compared with physical disability earlier in the disease… read more here.
Keywords: treatment; multiple sclerosis; treatment approaches; onset multiple ... See more keywords
Bringing the HEET: The Argument for High-Efficacy Early Treatment for Pediatric-Onset Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Neurotherapeutics"
DOI: 10.1007/s13311-017-0568-1
Abstract: Pediatric-onset multiple sclerosis (POMS) is rarer than adult-onset disease, and represents a different diagnostic and treatment challenge to clinicians. We review POMS clinical and radiographic presentations, and explore important differences between POMS and adult-onset MS… read more here.
Keywords: high efficacy; treatment; early treatment; efficacy early ... See more keywords
A systematic review and quantitative synthesis of the long-term psychiatric sequelae of pediatric autoimmune encephalitis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2022.04.027
Abstract: BACKGROUND Long-term neuropsychiatric sequelae of autoimmune encephalitis (AE) remain understudied, particularly in pediatric-onset AE. We aimed to synthesize the published data on ongoing psychiatric symptoms in pediatric-onset AE. METHODS The Pubmed, PyscINFO, Web of Science… read more here.
Keywords: quantitative synthesis; term; autoimmune encephalitis; pediatric onset ... See more keywords
Early-Onset Noncommunicable Disease and Multimorbidity Among Adults With Pediatric-Onset Disabilities.
Sign Up to like & getrecommendations! Published in 2019 at "Mayo Clinic proceedings"
DOI: 10.1016/j.mayocp.2019.07.010
Abstract: OBJECTIVE To determine the prevalence of major noncommunicable diseases among young adults with pediatric-onset disabilities (PoDs) compared with young adults without PoDs. PATIENTS AND METHODS Data were obtained from the Optum Clinformatics Data Mart, a… read more here.
Keywords: disease; multimorbidity; noncommunicable diseases; pediatric onset ... See more keywords
Reduced quality of life in a pediatric-onset Neuromyelitis optica spectrum disorders cohort.
Sign Up to like & getrecommendations! Published in 2021 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2021.103252
Abstract: BACKGROUND Neuromyelitis optica spectrum disorders (NMOSD) is a severe condition associated with high disability and low quality of life (QoL) in adults. Since this evaluation had been rarely perfomed in children, this study aimed to… read more here.
Keywords: neuromyelitis optica; optica spectrum; quality life; life ... See more keywords