Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.0595
Abstract: Key Points Question What is the risk of cancer among patients with pediatric-onset inflammatory bowel disease (IBD)? Findings This meta-analysis of 5 unselected, population-based cohort studies comprising 19 812 individuals found a 2.4-fold increased rate of… read more here.
Keywords: pediatric onset; onset inflammatory; cancer among; patients pediatric ... See more keywords
Effect of Dimethyl Fumarate vs Interferon β-1a in Patients With Pediatric-Onset Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.30439
Abstract: This randomized clinical trial investigates the efficacy and safety of dimethyl fumarate vs interferon β-1a for treatment of pediatric-onset multiple sclerosis. read more here.
Keywords: onset multiple; pediatric onset; multiple sclerosis; dimethyl fumarate ... See more keywords
miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.786
Abstract: Onset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped‐MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small noncoding… read more here.
Keywords: contributions pediatric; mirna contributions; multiple sclerosis; onset multiple ... See more keywords
Determining the time to cholangiocarcinoma in pediatric-onset PSC-IBD.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12443
Abstract: Primary sclerosing cholangitis (PSC) is a risk factor for cholangiocarcinoma. When a child is diagnosed with both PSC and inflammatory bowel disease (IBD), evidence-based information on counseling families and risk management of developing cholangiocarcinoma is… read more here.
Keywords: pediatric onset; psc ibd; time; cholangiocarcinoma ... See more keywords
Pediatric Onset of Generalized Dystonia, Cognitive Impairment, and Dysmorphic Features in a Patient Carrying Compound Heterozygous GNAL Mutations
Sign Up to like & getrecommendations! Published in 2024 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.14124
Abstract: Variants in GNAL have been mostly associated to adult-onset focal dystonia, involving laryngeal and craniocervical regions with superimposed tremor, being inherited in an autosomal dominant manner with reduced penetrance. 1 To date, biallelic variants in… read more here.
Keywords: pediatric onset; cognitive impairment; dystonia cognitive; onset generalized ... See more keywords
Substantia Nigra as Brainstem Signature in Pediatric-Onset Huntington's Disease: The RAREST-JHD Study.
Sign Up to like & getrecommendations! Published in 2025 at "Movement disorders clinical practice"
DOI: 10.1002/mdc3.70382
Abstract: BACKGROUND Pediatric-onset Huntington's disease (POHD) is usually associated with signs and symptoms of parkinsonism and dystonia predominating on chorea, which is typical of adult-onset HD (AOHD). Brain changes responsible of such an atypical POHD phenotype… read more here.
Keywords: pediatric onset; huntington disease; onset huntington; huntington ... See more keywords
Oncogenic rickets diagnosed at age 8 and the risk of persistent rickets: a rare case of pediatric-onset tumor-induced osteomalacia
Sign Up to like & getrecommendations! Published in 2025 at "Osteoporosis International"
DOI: 10.1007/s00198-025-07469-2
Abstract: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by excess fibroblast growth factor 23 (FGF23), leading to hypophosphatemia and osteomalacia. It typically manifests in adulthood, with pediatric cases being exceedingly rare. Early diagnosis is… read more here.
Keywords: induced osteomalacia; pediatric onset; tumor; case ... See more keywords
Microvascular decompression for pediatric onset trigeminal neuralgia: patterns and variation
Sign Up to like & getrecommendations! Published in 2022 at "Child's Nervous System"
DOI: 10.1007/s00381-021-05432-0
Abstract: Pediatric trigeminal neuralgia has been rarely reported in the literature, which were only 28 cases. Although microvascular decompression (MVD) has been widely accepted as effective therapy for trigeminal neuralgia, the etiology and surgical treatment of… read more here.
Keywords: trigeminal neuralgia; neuralgia; microvascular decompression; pediatric onset ... See more keywords
Three-year experience with GLP-2 analog in intestinal rehabilitation for pediatric-onset short bowel syndrome
Sign Up to like & getrecommendations! Published in 2025 at "Pediatric Surgery International"
DOI: 10.1007/s00383-025-06154-z
Abstract: To evaluate the impact of three-year Glucagon-like peptide 2 (GLP-2) analog therapy on parenteral nutrition (PN) dependency, intestinal rehabilitation, and quality of life in pediatric-onset short bowel syndrome (SBS). Between August 2021 and December 2024,… read more here.
Keywords: pediatric onset; glp analog; three year; intestinal rehabilitation ... See more keywords
Treatment of pediatric-onset lupus nephritis: a proposal of optimal therapy
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-017-1381-1
Abstract: Lupus nephritis (LN) is one of the major clinical manifestations of systemic lupus erythematosus (SLE) which occurs frequently in the early stages of pediatric-onset cases. Since SLE is a chronic disease associated with frequent disease… read more here.
Keywords: therapy; lupus nephritis; treatment; pediatric onset ... See more keywords
Two Sides of the Same Coin: Pediatric-Onset and Adult-Onset Common Variable Immune Deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-017-0415-5
Abstract: PurposeCommon variable immunodeficiency (CVID) is a complex, heterogeneous immunodeficiency characterized by hypogammaglobulinemia, recurrent infections, and poor antibody response to vaccination. While antibiotics and immunoglobulin prophylaxis have significantly reduced infectious complications, non-infectious complications of autoimmunity, inflammatory… read more here.
Keywords: cvid patients; adult onset; adult; pediatric onset ... See more keywords