Clinical Prognostic Factors and Outcome in Pediatric Osteosarcoma: Effect of Delay in Local Control and Degree of Necrosis in a Multidisciplinary Setting in Lebanon
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DOI: 10.1200/jgo.17.00241
Abstract: PURPOSE Outcomes in pediatric osteosarcoma have dramatically improved over the past few decades, with overall survival rates of 70% and 30% for patients with localized and metastatic disease, respectively. PATIENTS AND METHODS We retrospectively reviewed… read more here.
Keywords: pediatric osteosarcoma; necrosis; degree necrosis; disease ... See more keywords
Novel insights and therapeutic interventions for pediatric osteosarcoma.
Sign Up to like & getrecommendations! Published in 2017 at "Future oncology"
DOI: 10.2217/fon-2016-0261
Abstract: High-grade osteosarcomas are the most common primary malignant tumors of bone. With complete surgical resection and multi-agent chemotherapy up to 70% of patients with high-grade osteosarcomas and localized extremity tumors can become long-term survivors. The… read more here.
Keywords: therapeutic interventions; novel insights; interventions pediatric; insights therapeutic ... See more keywords
Predictive value of the systemic immune-inflammation index for cancer-specific survival of osteosarcoma in children
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DOI: 10.3389/fpubh.2022.879523
Abstract: Background Osteosarcoma (OS) is the primary malignant bone tumor that most commonly affects children and adolescents. Recent years effective chemotherapy have improved the 5-year survival in osteosarcoma patients to up to 60%-70%. Still, there is… read more here.
Keywords: index; osteosarcoma; survival; value ... See more keywords
In Situ Analysis of mTORC1/C2 and Metabolism-Related Proteins in Pediatric Osteosarcoma
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DOI: 10.3389/pore.2022.1610231
Abstract: Activation of the mTOR pathway has been observed in osteosarcoma, however the inhibition of mammalian target of rapamycin (mTOR) complex 1 has had limited results in osteosarcoma treatment. Certain metabolic pathways can be altered by… read more here.
Keywords: certain metabolic; expression; situ analysis; pediatric osteosarcoma ... See more keywords