TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT
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DOI: 10.15252/emmm.202215859
Abstract: In some types of cancer, telomere length is maintained by the alternative lengthening of telomeres (ALT) mechanism. In many ALT cancers, the α‐thalassemia/mental retardation syndrome X‐linked (ATRX) gene is mutated leading to the conclusion that… read more here.
Keywords: atrx; pediatric osteosarcomas; alt; top3a amplification ... See more keywords