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Published in 2019 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000634
Abstract: PURPOSE OF REVIEW IL-18 is a pleiotropic cytokine involved in the regulation of innate and adaptive immune responses. IL-18 pro-inflammatory activities are finely regulated in vivo by the inhibitory effects of the soluble IL-18-binding protein…
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Keywords:
rheumatic diseases;
pediatric rheumatic;
interleukin pediatric;
rheumatology ... See more keywords
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Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.6436
Abstract: Pediatric rheumatic diseases (PRD) have an important impact on different aspects of the patients’ and caregivers’ life, such as physical, emotional, economic, and social. Some studies have shown that parents of patients with PRD have…
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Keywords:
diagnosis;
pediatric rheumatic;
thu0509 impact;
impact ... See more keywords
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Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.820586
Abstract: JAK-inhibitors are small molecules blocking the JAK-STAT pathway that have proven effective in the treatment of different immune-mediated diseases in adults and juvenile idiopathic arthritis (JIA). Aim of Study To evaluate the safety and efficacy…
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Keywords:
rheumatic diseases;
efficacy tofacitinib;
pediatric rheumatic;
safety efficacy ... See more keywords