3D surgical planning of pediatric tumors: a review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Computer Assisted Radiology and Surgery"
DOI: 10.1007/s11548-022-02557-8
Abstract: 3D surgical planning for the treatment of tumors in pediatrics using different neuroimaging methods is witnessing an accelerating and dynamic development. Until now, there have been many reports on the use of 3D printing techniques… read more here.
Keywords: surgical planning; planning pediatric; planning; pediatric tumors ... See more keywords
C-MET as a potential target therapy toward personalized therapy in some pediatric tumors: An overview.
Sign Up to like & getrecommendations! Published in 2018 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2018.08.007
Abstract: Althoughpediatric tumors represent less than 1% of all new cancer diagnoses, they still rank the second in the list of disease-related morbidity and mortality in children in the US. Combining biomarker-driven targeted therapy with individualized… read more here.
Keywords: potential target; met potential; target therapy; pediatric tumors ... See more keywords
Analysis of person-hours required for proton beam therapy for pediatric tumors
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rrad022
Abstract: Abstract Proton beam therapy (PBT) is effective for pediatric tumors, but patients may require sedation and other preparations, which extend the treatment time. Pediatric patients were classified into sedation and non-sedation cases. Adult patients were… read more here.
Keywords: hours required; person; proton beam; beam therapy ... See more keywords
Immunotherapy approaches for rare pediatric solid tumors: advances and future directions
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001206
Abstract: Purpose of review Immunotherapy for pediatric tumors is rapidly evolving. From major successes in pediatric hematologic malignancies, immunotherapy utility increased in the pediatric solid tumor landscape. Numerous pediatric solid tumors are defined as rare with… read more here.
Keywords: pediatric rare; pediatric solid; immunotherapy approaches; solid tumors ... See more keywords
Epigenetic Therapies.
Sign Up to like & getrecommendations! Published in 2024 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041637
Abstract: Epigenetic therapies are emerging for pediatric cancers. Due to the relatively low mutational burden in pediatric tumors, epigenetic dysregulation and differentiation blockade is a hallmark of oncogenesis in some childhood cancers. By targeting epigenetic regulators… read more here.
Keywords: pediatric tumors; oncogenic fusion; epigenetic dysregulation; epigenetic therapies ... See more keywords
Long‐term follow‐up after proton beam therapy for pediatric tumors: a Japanese national survey
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Science"
DOI: 10.1111/cas.13140
Abstract: Proton beam therapy (PBT) is a potential new alternative to treatment with photon radiotherapy that may reduce the risk of late toxicity and secondary cancer, especially for pediatric tumors. The goal of this study was… read more here.
Keywords: beam therapy; secondary tumors; long term; pediatric tumors ... See more keywords
Abstract 1372: Development of a multi-omic spatial phenotyping assay for affirmative detection of CAR-T cells in the tumor immune microenvironment of solid pediatric tumors
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-1372
Abstract: Certain pediatric cancers, like blood leukemia, have shown high cure rates, but effective treatments of solid tumors remain elusive and survival rates for affected children remain low. While CAR-T therapy has demonstrated success in treating… read more here.
Keywords: pediatric tumors; detection; car; tumor ... See more keywords
Abstract B046: Filtering artifactual signal for DNA-methylation arrays in pediatric tumors: A benchmarking of preprocessing algorithms
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.pediatric25-b046
Abstract: Methylome analysis holds promise in cancer research, enabling a better understanding of tumor biology and epigenetic regulation. Array-based methylation profiling can be compromised by recurrent somatic genetic alterations in cancer, which can cause nonspecific (off-target)… read more here.
Keywords: pediatric tumors; cancer; methylation; artifactual signal ... See more keywords
Phase I study of mitoxantrone hydrochloride liposome in relapsed and refractory pediatric tumors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.10049
Abstract: 10049 Background: Compared with solvent-based mitoxantrone, mitoxantrone hydrochloride liposome has been found to reduce bone marrow toxicity. This open-label, single-arm phase I clinical trial was designed to evaluate the safety and efficacy of mitoxantrone hydrochloride… read more here.
Keywords: mitoxantrone liposome; pediatric tumors; hydrochloride liposome; mitoxantrone hydrochloride ... See more keywords
Management of Pediatric Tumors With Vascular Extension
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2021.753232
Abstract: Background: Pediatric tumors can present with vascular extension to the inferior vena cava and right atrium, which impacts the surgical strategy and can be challenging during surgical treatment. Wilms tumor (WT) is the most common… read more here.
Keywords: tumors vascular; extension; cardiac bypass; vascular extension ... See more keywords