Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.13968
Abstract: This cohort study evaluates the feasibility and utility of incorporating comparative gene expression information into the precision medicine framework for difficult-to-treat pediatric and young adult patients with cancer. read more here.
Keywords: young adult; pediatric young; patients cancer; difficult treat ... See more keywords
The journey to CAR T cell therapy: the pediatric and young adult experience with relapsed or refractory B-ALL
Sign Up to like & getrecommendations! Published in 2019 at "Blood Cancer Journal"
DOI: 10.1038/s41408-018-0164-6
Abstract: Outcomes of pediatric and young adult patients diagnosed with acute lymphoblastic leukemia (ALL) have improved significantly in the past few decades. Treatment advances have provided 5-year survival rates ranging from 78 to 91% depending on… read more here.
Keywords: car cell; cell therapy; pediatric young; cell ... See more keywords
Modernizing Our Understanding of Total Hip Arthroplasty in the Pediatric and Young Adult Patient: A Single-center Experience
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Pediatric Orthopaedics"
DOI: 10.1097/bpo.0000000000002316
Abstract: Introduction: Pediatric hip disorders represent a broad range of pathology and remain a significant source of morbidity for children and young adults. Surgical intervention is often required for joint preservation, but when salvage is not… read more here.
Keywords: pediatric young; hip; total hip; tha ... See more keywords
PD14-01 INCREASED RISK OF NEW PERSISTENT OPIOID USE IN PEDIATRIC AND YOUNG ADULT UROLITHIASIS PATIENTS PRESCRIBED OPIOIDS AT PRESENTATION
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000848.01
Abstract: INTRODUCTION AND OBJECTIVE:Pediatric and young adults are a vulnerable patient population for development of addiction after opioid exposure. The incidence of pediatric urolithiasis has been steadi... read more here.
Keywords: pd14 increased; pediatric young; increased risk; urolithiasis ... See more keywords
Frequency and Severity of Hypothyroidism During TKI Therapy in the Pediatric and Young Adult Population
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002527
Abstract: Tyrosine kinase inhibitors that target vascular endothelial growth factor receptor [VEGFR-TKI] are a class of targeted therapies approved for treatment of several malignancies and are increasingly used in the pediatric population. Development of hypothyroidism during… read more here.
Keywords: young adult; vegfr tki; therapy; tki therapy ... See more keywords
Immune responses to hepatitis B vaccination after hematopoietic stem cell transplantation in pediatric and young adult patients
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Transplantation"
DOI: 10.1111/ctr.14024
Abstract: Hematopoietic stem cell transplantation (HSCT) recipients require hepatitis B (HBV) revaccination. Hepatitis B surface antibody (anti‐HBs) seroconversion rates after revaccination range from 64% to 79% in these patients. The seroconversion rate and factors associated with… read more here.
Keywords: young adult; pediatric young; cell transplantation; stem cell ... See more keywords
Impact of COVID-19 in Pediatric Patients and Young Adults with Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2022 at "GE Portuguese Journal of Gastroenterology"
DOI: 10.1159/000522073
Abstract: Introduction: Acute COVID-19 in pediatric and young adult patients tends to be milder in severity compared to adult infection. Recent studies seem to show that inflammatory bowel disease (IBD) patients are at no greater risk… read more here.
Keywords: covid pediatric; young adult; adult; disease ... See more keywords
Patient-reported quality of life (QOL) following CTL019 in pediatric and young adult patients (pts) with relapsed/refractory (r/r) b-cell acute lymphoblastic leukemia (B-ALL).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.10523
Abstract: 10523Background: The global ELIANA trial (NCT02435849) evaluates the efficacy and safety of CTL019, a single infusion of genetically modified autologous chimeric antigen receptor–expressing T cells targeting CD19+ cells in pediatric and young adult r/r B-ALL… read more here.
Keywords: young adult; following ctl019; infusion; pediatric young ... See more keywords
Three-Year Update of Tisagenlecleucel in Pediatric and Young Adult Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia in the ELIANA Trial
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.22.00642
Abstract: Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet… read more here.
Keywords: young adult; year; adult patients; trial ... See more keywords
Estimation of Total Costs in Pediatric and Young Adult Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia Receiving Tisagenlecleucel from a U.S. Hospital's Perspective.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of managed care & specialty pharmacy"
DOI: 10.18553/jmcp.2020.20052
Abstract: BACKGROUND Tisagenlecleucel was approved for the treatment of pediatric and young adult patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (ALL) based on the pivotal ELIANA trial. OBJECTIVE To comprehensively evaluate the total costs associated… read more here.
Keywords: young adult; tisagenlecleucel treatment; treatment; pediatric young ... See more keywords
Adoptive Cell Therapy in Pediatric and Young Adult Solid Tumors: Current Status and Future Directions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.846346
Abstract: Advances from novel adoptive cellular therapies have yet to be fully realized for the treatment of children and young adults with solid tumors. This review discusses the strategies and preliminary results, including T-cell, NK-cell and… read more here.
Keywords: therapy pediatric; cell; cell therapy; solid tumors ... See more keywords