Synthesis, antimicrobial activity and conformational analysis of the class IIa bacteriocin pediocin PA-1 and analogs thereof
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DOI: 10.1038/s41598-018-27225-3
Abstract: The antimicrobial peptide pediocin PA-1 is a class IIa bacteriocin that inhibits several clinically relevant pathogens including Listeria spp. Here we report the synthesis and characterization of whole pediocin PA-1 and novel analogs thereof using… read more here.
Keywords: pediocin; analogs thereof; bacteriocin; iia bacteriocin ... See more keywords
An oxidation resistant pediocin PA-1 derivative and penocin A display effective anti-Listeria activity in a model human gut environment
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DOI: 10.1080/19490976.2021.2004071
Abstract: ABSTRACT Pediocin PA-1 is a class IIa bacteriocin that is particularly effective against the foodborne pathogen Listeria monocytogenes. The loss of activity of PA-1 pediocin due to methionine oxidation is one of the challenges that… read more here.
Keywords: penocin; anti listeria; listeria activity; activity ... See more keywords
Structural Basis of Pore Formation in the Mannose Phosphotransferase System by Pediocin PA-1
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DOI: 10.1128/aem.01992-21
Abstract: Listeria monocytogenes is a ubiquitous microorganism responsible for listeriosis, a rare but severe disease in humans, who become infected by ingesting contaminated food products (i.e., dairy, meat, fish, and vegetables): the disease has a fatality… read more here.
Keywords: listeria monocytogenes; pediocin; phosphotransferase system; mannose phosphotransferase ... See more keywords