Mechanisms of decreased cholinergic arousal in focal seizures: In vivo whole-cell recordings from the pedunculopontine tegmental nucleus
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2018.11.008
Abstract: &NA; Focal limbic seizures often impair consciousness/awareness with major negative impact on quality of life. Recent work has shown that limbic seizures depress brainstem arousal systems, including reduced action potential firing in a key node:… read more here.
Keywords: whole cell; cholinergic neurons; pedunculopontine tegmental; limbic seizures ... See more keywords
Suppressive effect of the swallowing reflex by stimulation of the pedunculopontine tegmental nucleus
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DOI: 10.1016/j.neures.2020.07.001
Abstract: This study investigates whether the swallowing reflex is modulated by stimulation of the pedunculopontine tegmental nucleus (PTg). Sprague-Dawley rats under urethane anesthesia were used. The swallowing reflex was induced by electrical stimulation of the superior… read more here.
Keywords: stimulation pedunculopontine; stimulation; pedunculopontine tegmental; tegmental nucleus ... See more keywords
The possible role of pedunculopontine tegmental nucleus (PPT) opioid receptors in the cardiovascular responses in normotensive and hemorrhagic hypotensive rats
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2022.2050744
Abstract: ABSTRACT Background The pedunculopontine tegmental nucleus (PPT) is involved in cardiovascular regulation. The presence of mu (μ) opioid receptors in the PPT nucleus has been determined. In the present study, the role of this nucleus… read more here.
Keywords: role; pedunculopontine tegmental; group; ppt ... See more keywords
Hemisphere-specific characterization of projections from the Pedunculopontine Tegmental Nucleus to Substantia Nigra pars Compacta dopaminergic neurons
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DOI: 10.1152/physiol.2023.38.s1.5732734
Abstract: The neurotransmitter dopamine has been shown to be implicated in motivation and reward, notably in the nigrostriatal dopaminergic pathway. Within this pathway, our research focuses on the synapse between the midbrain regions pedunculopontine tegmental nucleus… read more here.
Keywords: nigra pars; pedunculopontine tegmental; substantia nigra; tegmental nucleus ... See more keywords
Behavioral Reaction and c-fos Expression after Opioids Injection into the Pedunculopontine Tegmental Nucleus and Electrical Stimulation of the Ventral Tegmental Area
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010512
Abstract: The pedunculopontine tegmental nucleus (PPN) regulates the activity of dopaminergic cells in the ventral tegmental area (VTA). In this study, the role of opioid receptors (OR) in the PPN on motivated behaviors was investigated by… read more here.
Keywords: pedunculopontine tegmental; tegmental area; tegmental nucleus; ventral tegmental ... See more keywords