Carbon Dots Based Nanoscale Covalent Organic Frameworks for Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202004680
Abstract: Covalent organic frameworks (COFs) have attracted much attention for various applications, while developing COFs with biomedical functions remains a big challenge. Most COFs are built purely from organic molecules, no carbon dots (CDs)‐based COFs have… read more here.
Keywords: photodynamic therapy; covalent organic; carbon dots; organic frameworks ... See more keywords
Oil Core-PEG Shell Nanocarriers for In Vivo MRI Imaging.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801313
Abstract: Oil-in-water emulsions represent a promising carrier for in vivo imaging because of the possibility to convey poorly water-soluble species. To promote accumulation at the tumor site and prolong circulation time, reduction of carrier size and… read more here.
Keywords: shell; oil core; peg shell; peg ... See more keywords
Peptidic Monodisperse PEG "Comb" as Multifunctional "Add-On" Module for Imaging-Traceable and Thermo-Responsive Theranostics.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901331
Abstract: Monodisperse polyethylene glycols-modified (M-PEGylated) biomaterials exhibit high structural accuracy, biocompatibility, and fine-tunable physicochemical properties. To develop "smart" drug delivery systems in a controllable and convenient manner, a peptidic M-PEG "comb" with fluorinated L-lysine side chains… read more here.
Keywords: add module; thermo responsive; peg; peg comb ... See more keywords
Poly Ethylene Glycol (PEG)-based Hydrogels for Drug Delivery in Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300105
Abstract: Hydrogel-based drug delivery systems (DDSs) can leverage therapeutically beneficial outcomes in cancer therapy. In this domain, polyethylene glycol (PEG) has become increasingly popular as a biomedical polymer and has found clinical use. Owing to their… read more here.
Keywords: peg; drug; cancer therapy; drug delivery ... See more keywords
PEG‐Like Brush Polymer Conjugate of RNA Aptamer That Shows Reversible Anticoagulant Activity and Minimal Immune Response
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202107852
Abstract: Ribonucleic acid (RNA) therapeutics are an emerging class of drugs. RNA aptamers are of significant therapeutic and clinical interest because their activity can be easily reversed in vivo—a useful feature that is difficult to achieve… read more here.
Keywords: polymer; rna; rna aptamer; peg ... See more keywords
PEG Modified CsPbIBr2 Perovskite Film for Efficient and Stable Solar Cells
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.202000537
Abstract: Cesium lead mixed‐halide perovskite (CsPbIBr2), as one of the all‐inorganic perovskites, has attracted great attention owing to its great ambient stability and suitable bandgap. Unfortunately, due to its low film coverage, high density of defects… read more here.
Keywords: perovskite; peg modified; film; cspbibr2 ... See more keywords
Phase 1 trial of ADI‐PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.4446
Abstract: Arginine depletion interferes with pyrimidine metabolism and DNA damage repair pathways. Preclinical data demonstrated that depletion of arginine by PEGylated arginine deiminase (ADI‐PEG 20) enhanced liposomal doxorubicin (PLD) cytotoxicity in cancer cells with argininosuccinate synthase… read more here.
Keywords: liposomal doxorubicin; solid tumors; adi peg; metastatic solid ... See more keywords
Catalytic Activation of Esterases by PEGylation for Polyester Synthesis
Sign Up to like & getrecommendations! Published in 2019 at "ChemCatChem"
DOI: 10.1002/cctc.201900451
Abstract: In this work we explored PEGylation as an efficient strategy to improve esterase's catalytic performance. For this, we PEGylated three esterases, namely lipase from Candida antarctica B (CALB), lipase from Thermomyces lanuginosus (TL) and cutinase… read more here.
Keywords: calb; cutinase; lipase; activity ... See more keywords
PEGylated Dendritic Polyglycerol Conjugate Delivers Doxorubicin to the Parasitophorous Vacuole in Leishmania infantum Infections.
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201700098
Abstract: Most drugs against visceral leishmaniasis must be administered parenterally. A controlled drug release at the target site can improve the efficacy and toxicity of antileishmanial drugs in clinical use. Amastigotes live and grow inside the… read more here.
Keywords: pegylated dendritic; conjugate; dendritic polyglycerol; parasitophorous vacuole ... See more keywords
Photolithographically Patterned Cell-Repellent PEG-b-PTHPMA Diblock Copolymer for Guided Cell Adhesion and Growth.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200301
Abstract: Surfaces for guided cell adhesion and growth are indispensable in several diagnostic and therapeutic applications. Towards this direction, four diblock copolymers comprising polyethylene glycol (PEG) and poly(2-tetrahydropyranyl methacrylate) (PTHPMA) were synthesized employing PEG macroinitiators of… read more here.
Keywords: cell adhesion; peg; cell; adhesion growth ... See more keywords
HPMA‐PEG Surfmers and Their Use in Stabilizing Fully Biodegradable Polymer Nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular Chemistry and Physics"
DOI: 10.1002/macp.201700380
Abstract: The most adopted methods to produce polymer nanoparticles (NPs) for medical and pharmaceutical applications use surfactants that are toxic and physically adsorbed to the NPs, with the risk of desorption and insurgence of side effects.… read more here.
Keywords: polymer; hpma peg; surfmers use; polymer nanoparticles ... See more keywords