Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202200060
Abstract: Macrophages (Mφs) are characterized by remarkable plasticity, an essential component of chronic inflammation. Thus, an appropriate and timely transition from proinflammatory (M1) to anti-inflammatory (M2) Mφs during wound healing is vital to promoting resolution of… read more here.
Keywords: wound healing; cutaneous wound; peg hydrogels; polarization ... See more keywords
Glutathione-Conjugated Hydrogels: Flexible Vehicles for Personalized Treatment of Bacterial Infections.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical research"
DOI: 10.1007/s11095-021-03057-1
Abstract: PURPOSE Skin and soft tissue infections are increasingly prevalent and often complicated by potentially fatal therapeutic hurdles, such as poor drug perfusion and antibiotic resistance. Delivery vehicles capable of versatile loading may improve local bioavailability… read more here.
Keywords: peg hydrogels; gsh peg; glutathione conjugated; conjugated hydrogels ... See more keywords
Enhanced stem cell retention and antioxidative protection with injectable, ROS-degradable PEG hydrogels.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120377
Abstract: Poly(ethylene glycol) (PEG) hydrogels crosslinked with enzyme-cleavable peptides are promising biodegradable vehicles for therapeutic cell delivery. However, peptide synthesis at the level required for bulk biomaterial manufacturing is costly, and fabrication of hydrogels from scalable,… read more here.
Keywords: stem cell; peg hydrogels; ros degradable; stem ... See more keywords
Placenta Powder-Infused Thiol-Ene PEG Hydrogels as Potential Tissue Engineering Scaffolds
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01355
Abstract: Human placenta is a source of extracellular matrix for tissue engineering. In this study, placenta powder (PP), made from decellularized human placenta, was physically incorporated into synthetic poly(ethylene glycol) (PEG)-based hydrogels via UV-initiated thiol-ene coupling… read more here.
Keywords: tissue engineering; modpeg hydrogels; peg hydrogels; placenta powder ... See more keywords
Full Poly(ethylene glycol) Hydrogels with High Ductility and Self-Recoverability.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c08716
Abstract: Energy dissipation is a common mechanism to improve the ductility of polymeric hydrogels. However, for poly(ethylene glycol) (PEG) hydrogels, it is not easy to dissipate energy as polymer chains are dispersed in water without strong… read more here.
Keywords: ductility self; peg hydrogels; self recoverability; peg ... See more keywords
Bacterial Adhesion Is Affected by the Thickness and Stiffness of Poly(ethylene glycol) Hydrogels.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b12145
Abstract: Despite lacking visual, auditory, and olfactory perception, bacteria sense and attach to surfaces. Many factors, including the chemistry, topography, and mechanical properties of a surface, are known to alter bacterial attachment, and in this study,… read more here.
Keywords: peg hydrogels; poly ethylene; ethylene glycol; soft hydrogels ... See more keywords
Investigation of the 3D Printability of Covalently Cross-Linked Polypeptide-Based Hydrogels
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c05873
Abstract: The 3D printability of poly(l-lysine-ran-l-alanine) and four-arm poly(ethylene glycol) (P(KA)/4-PEG) hydrogels as 3D biomaterial inks was investigated using two approaches to develop P(KA)/4-PEG into 3D biomaterial inks. Only the “composite microgel” inks were 3D printable.… read more here.
Keywords: biomaterial inks; printability; cross linked; covalently cross ... See more keywords
Construction of porous sponge-like PVA-CMC-PEG hydrogels with pH-sensitivity via phase separation for wound dressing
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Polymeric Materials and Polymeric Biomaterials"
DOI: 10.1080/00914037.2019.1581200
Abstract: Abstarct To improve mechanical strength, polyvinyl alcohol hydrogels were often prepared through freeze-thaw method. However, they usually exhibited micropores limiting their applications. Hence, macroporous polyvinyl alcohol-carboxymethyl cellulose-polyethylene glycol (PVA-CMC-PEG) hydrogels were prepared through phase separation.… read more here.
Keywords: cmc peg; pva cmc; peg hydrogels;