Estrone-Conjugated PEGylated Liposome Co-Loaded Paclitaxel and Carboplatin Improve Anti-Tumor Efficacy in Ovarian Cancer and Reduce Acute Toxicity of Chemo-Drugs
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DOI: 10.2147/ijn.s362263
Abstract: Purpose Ovarian cancer is the most lethal gynecologic malignancy. The combination of paclitaxel (PTX) and carboplatin (CBP) is the first-line remedy for clinical ovarian cancer. However, due to the limitations of adverse reaction and lacking… read more here.
Keywords: cbp; peg lip; lip ptx; ptx cbp ... See more keywords
Liposomes Loaded with Everolimus and Coated with Hyaluronic Acid: A Promising Approach for Lung Fibrosis
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DOI: 10.3390/ijms22147743
Abstract: Chronic lung allograft dysfunction (CLAD) and interstitial lung disease associated with collagen tissue diseases (CTD-ILD) are two end-stage lung disorders in which different chronic triggers induce activation of myo-/fibroblasts (LFs). Everolimus, an mTOR inhibitor, can… read more here.
Keywords: lip ha400kda; loaded everolimus; hyaluronic acid; peg lip ... See more keywords
Safety, Stability, and Therapeutic Efficacy of Long-Circulating TQ-Incorporated Liposomes: Implication in the Treatment of Lung Cancer
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DOI: 10.3390/pharmaceutics14010153
Abstract: Thymoquinone (TQ), which is one of the main bioactive constituents of Nigella sativa seeds, has demonstrated its potential against various cancer models. The poor solubility of TQ in aqueous solution limits its uses in clinical… read more here.
Keywords: lung cancer; cancer; efficacy; treatment lung ... See more keywords
Impact of PEGylated Liposomal Doxorubicin and Carboplatin Combination on Glioblastoma
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DOI: 10.3390/pharmaceutics14102183
Abstract: Glioblastoma is an incurable cancer with a 5-year survival chance of less than 5%. Chemotherapy is a therapeutic approach to treating the disease; however, due to the presence of the blood–brain barrier (BBB), the probability… read more here.
Keywords: carboplatin; dox; doxorubicin; lip dox ... See more keywords