Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates.
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DOI: 10.1007/978-1-4939-8796-2_16
Abstract: Methionine (MET) is a general metabolic therapeutic target in cancer, whereby cancer cells have an elevated requirement for MET, termed MET dependence. We have developed recombinant L-methionine α-deamino-γ-mercaptomethane lyase (recombinant methioninase [rMETase, EC 4.4.1.11]) as… read more here.
Keywords: megc peg; peg rmetase; toxicity; recombinant methioninase ... See more keywords