Structure-based antigenic epitope and PEGylation improve the efficacy of staphylokinase
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DOI: 10.1186/s12934-017-0801-y
Abstract: Staphylokinase (Sak) holds promise for use in thrombolytic therapy for acute myocardial infarction. However, its immunogenicity is a major disadvantage under clinical conditions. PEGylation has become a sophisticated method to decrease that immunogenicity. In this… read more here.
Keywords: sak; peg sak; sak c104r; pegylation ... See more keywords