Achieving efficacy in subjects with sustained pegvaliase-neutralizing antibody responses.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular genetics and metabolism"
DOI: 10.1016/j.ymgme.2021.09.006
Abstract: Pegvaliase (Palynziq®) is an enzyme substitution therapy using PEGylated recombinant Anabaena variabilis phenylalanine ammonia lyase (PAL) to reduce blood phenylalanine (Phe) levels in adults with phenylketonuria (PKU). In Phase 3 clinical studies, all subjects treated… read more here.
Keywords: pegvaliase neutralizing; nab titers; pegvaliase; blood phe ... See more keywords