Targeting the resolution pathway of inflammation using Ac2–26 peptide-loaded PEGylated lipid nanoparticles for the remission of rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2021 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2021.03.001
Abstract: Rheumatoid arthritis (RA) is a common autoimmune disease characterized by joint inflammation and immune dysfunction. Although various therapeutic approaches have been utilized for the treatment of RA in clinical applications, the low responsiveness of RA… read more here.
Keywords: peptide; targeting resolution; inflammation; pegylated lipid ... See more keywords
Potential enhancement of metformin hydrochloride in solidified reverse micellar solution-based PEGylated lipid nanoparticles targeting therapeutic efficacy in diabetes treatment
Sign Up to like & getrecommendations! Published in 2022 at "Heliyon"
DOI: 10.1016/j.heliyon.2022.e09099
Abstract: Metformin hydrochloride (MH) is a widely used oral biguanide antihyperglycemic (antidiabetic) drug with poor bioavailability which necessitates the development of novel drug delivery systems such as PEGylated solid lipid nanoparticles for improving its therapeutic activity.… read more here.
Keywords: pegylated lipid; lipid nanoparticles; drug; spectroscopy ... See more keywords
Quantification of Anti-osteoporotic Anabolic Peptide in Stealth Lipid Nanovesicles through Validated RP-HPLC Method.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsac096
Abstract: BACKGROUND Teriparatide is a recombinant fragment of human parathyroid hormone, a potent osteoanabolic agent used for osteoporosis. OBJECTIVE The present study endeavored to develop a simple, rapid, and reliable RP-HPLC method for the determination of… read more here.
Keywords: pegylated lipid; lipid nanovesicles; quantification teriparatide; hplc method ... See more keywords