Optimized rapamycin-loaded PEGylated PLGA nanoparticles: Preparation, characterization and pharmacokinetics study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102144
Abstract: Abstract Rapamycin (RAP), an inhibitor of mTOR signaling pathway, has been widely used for its immunosuppressive activity over its anti-tumor and anti-inflammatory properties. The objective of this study was to encapsulate RAP into appropriately sized… read more here.
Keywords: pegylated plga; plga nanoparticles; rap; loaded pegylated ... See more keywords
Targeted delivery of resveratrol using PEGylated PLGA nanoparticles decorated with folic acid for cancer therapy: characterization, and in vitro studies
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2025.2562181
Abstract: Abstract Objective This study aimed to develop, characterize, and evaluate resveratrol-loaded pegylated PLGA [poly (lactic-co-glycolic acid)] nanoparticles with folate conjugation for improved drug delivery and cytotoxic efficacy against MCF7 breast cancer cells. Significance The significance… read more here.
Keywords: cancer; delivery; resveratrol; drug ... See more keywords
Design, Formulation and in vivo Evaluation of Novel Honokiol-Loaded PEGylated PLGA Nanocapsules for Treatment of Breast Cancer
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s241428
Abstract: Background Honokiol (HK) is a common herbal medicine extracted from magnolia plants. Low aqueous solubility and limited bioavailability of HK have hindered its clinical application, especially for cancer treatment. Nano-drug delivery system has the potential… read more here.
Keywords: treatment; loaded ncs; cancer; breast cancer ... See more keywords
Insight into Fucoidan-Based PEGylated PLGA Nanoparticles Encapsulating Methyl Anthranilic Acid: In Vitro Evaluation and In Vivo Anti-Inflammatory Study
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DOI: 10.3390/md20110694
Abstract: A potential fucoidan-based PEGylated PLGA nanoparticles (NPs) offering a proper delivery of N-methyl anthranilic acid (MA, a model of hydrophobic anti-inflammatory drug) have been developed via the formation of fucoidan aqueous coating surrounding PEGylated PLGA… read more here.
Keywords: fucoidan based; methyl anthranilic; anti inflammatory; based pegylated ... See more keywords