Biodistribution and Toxicity Assessment of Superparamagnetic Iron Oxide Nanoparticles In Vitro and In Vivo
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DOI: 10.1007/s11596-018-1989-8
Abstract: SummaryBiodistribution and toxicity assessment are critical for safe clinical use of newly developed medicines. Superparamagnetic iron oxide nanoparticles (SPION) are effective carriers for targeted drug delivery. This study aimed to examine the toxicity and biodistribution… read more here.
Keywords: spion pei; toxicity; iron; pei sirna ... See more keywords
Folate-targeted selenium nanoparticles deliver therapeutic siRNA to improve hepatocellular carcinoma therapy
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DOI: 10.1039/c8ra04204g
Abstract: To obtain a tumor targeting siRNA delivery vehicle for hepatocellular carcinoma treatments, functionalized selenium nanoparticles, Se–PEI–FA, were first prepared by decorating selenium nanoparticles with polycationic polymers, polyethylenimine (PEI), linked with folic acid (FA). FA functions… read more here.
Keywords: hepatocellular carcinoma; pei sirna; selenium nanoparticles; tumor ... See more keywords