Abstract OT-13-02: Bracelet-1 (pre0113): A study to assess overall response rate by inducing an inflammatory phenotype in metastatic breast cancer with the oncolytic reovirus pelareorep in combination with anti-PD-L1 avelumab and paclitaxel
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs20-ot-13-02
Abstract: Background: A randomized phase 2 study with the intravenously delivered oncolytic virus, pelareorep, in combination with paclitaxel (PTX) demonstrated a statistically significant improvement in overall survival (OS) from 10.4 months with PTX alone to 17.4… read more here.
Keywords: pelareorep; response; breast cancer; study ... See more keywords
Pelareorep to promote the expression of a IFN-gamma-related gene signature that predicts response to checkpoint blockade therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.3089
Abstract: 3089Background: A clinical study in patients (pts) with metastatic breast cancer (mBC) treated with pelareorep resulted in significant improvements in overall survival. Clinical studies with checkp... read more here.
Keywords: gamma related; expression ifn; promote expression; pelareorep promote ... See more keywords