Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation
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DOI: 10.1371/journal.pbio.3000837
Abstract: Amyloid-β (Aβ) accumulation in the brain is a hallmark of Alzheimer’s disease (AD) pathology. However, the molecular mechanism controlling microglial Aβ phagocytosis is poorly understood. Here we found that the E3 ubiquitin ligase Pellino 1… read more here.
Keywords: degradation; peli1 impairs; peli1; impairs microglial ... See more keywords