Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis.
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DOI: 10.1016/j.canlet.2019.02.014
Abstract: Evasion of apoptosis is a major contributing factor to the development of chemo- and radiotherapy resistance. Therefore, activation of non-apoptotic programmed cell death (PCD) could be an effective alternative against apoptosis-resistant cancers. In this study,… read more here.
Keywords: pyroptosis; targeting mir; pelp1; metformin induces ... See more keywords
Global Genomic and Proteomic Analysis Identified Critical Pathways Modulated by Proto-Oncogene PELP1 in TNBC
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DOI: 10.3390/cancers14040930
Abstract: Simple Summary The proto-oncogene PELP1 is commonly overexpressed in many cancers including triple negative breast cancer (TNBC). In this study, we utilized global proteomic and RNA-seq approaches to elucidate the molecular mechanisms by which PELP1… read more here.
Keywords: ribosomal proteins; expression; pelp1; tnbc ... See more keywords