Efficacy and Safety of K-877 (Pemafibrate), a Selective PPARα Modulator, in European Patients on Statin Therapy.
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DOI: 10.2337/dc21-1288
Abstract: OBJECTIVE High plasma triglyceride (TG) is an independent risk factor for cardiovascular disease. Fibrates lower TG levels through peroxisome proliferator-activated receptor α (PPARα) agonism. Currently available fibrates, however, have relatively low selectivity for PPARα. The… read more here.
Keywords: ppar; pemafibrate selective; ppar modulator; 877 pemafibrate ... See more keywords