Efficacy and safety of pembrolizumab monotherapy in patients with advanced thyroid cancer in the phase 2 KEYNOTE‐158 study
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DOI: 10.1002/cncr.34657
Abstract: The authors report results from the thyroid carcinoma cohort of the multicohort phase 2 KEYNOTE‐158 study (NCT02628067), which evaluated pembrolizumab monotherapy in patients with previously treated cancers. read more here.
Keywords: keynote 158; 158 study; phase keynote; pembrolizumab monotherapy ... See more keywords
Pembrolizumab Monotherapy Is Active in Metastatic Prostate Cancer.
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DOI: 10.1158/2159-8290.cd-rw2019-181
Abstract: In patients with metastatic castration-resistant prostate cancer, pembrolizumab showed efficacy. read more here.
Keywords: prostate cancer; pembrolizumab monotherapy; cancer; cancer pembrolizumab ... See more keywords
Post-Progression Survival Influences Overall Survival among Patients with Advanced Non-Small Cell Lung Cancer Undergoing First-Line Pembrolizumab Monotherapy
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DOI: 10.1159/000516745
Abstract: Background: Among patients with non-small cell lung cancer (NSCLC), the impact of first-line treatment on overall survival (OS) may be influenced by subsequent therapies. Thus, using patient-level data, we assessed the relationships of progression-free survival… read more here.
Keywords: first line; survival; pembrolizumab monotherapy;
Pembrolizumab (P) monotherapy in patients with previously treated metastatic high grade neuroendocrine neoplasms (HG-NENs).
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DOI: 10.1200/jco.2018.36.15_suppl.4104
Abstract: 4104Background: There is currently no standard therapy for metastatic HG-NENs after progression on platinum based therapy and available chemotherapy is of limited benefit. Given the promising activ... read more here.
Keywords: patients previously; monotherapy patients; pembrolizumab monotherapy; treated metastatic ... See more keywords
Association of High Neutrophil-to-Lymphocyte Ratio With Poor Outcomes of Pembrolizumab Therapy in High-PD-L1-expressing Non-small Cell Lung Cancer
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DOI: 10.21873/anticanres.13902
Abstract: Background: This study aimed to determine whether the neutrophil-to-lymphocyte ratio (NLR) reflected poor treatment benefits in patients with tumor proportion score (TPS) ≥50% and who under went first-line pembrolizumab monotherapy. Patients and Methods: This study… read more here.
Keywords: pembrolizumab monotherapy; neutrophil lymphocyte; lymphocyte ratio; non small ... See more keywords