Pembrolizumab for the treatment of Hodgkin Lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2020.1830056
Abstract: ABSTRACT Introduction Classic Hodgkin lymphoma (cHL) is a cancer of the immune system. Combination chemotherapy and radiation therapy result in high cure rate, nevertheless, up to a quarter of patients with advanced stage cHL may… read more here.
Keywords: pembrolizumab; pembrolizumab treatment; hodgkin lymphoma; chl ... See more keywords
Bilateral Corneal Graft Rejection Associated With Pembrolizumab Treatment.
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DOI: 10.1097/ico.0000000000002372
Abstract: PURPOSE To report the first case of corneal graft rejection presumably associated with pembrolizumab immunotherapy. METHODS Case report and literature review. RESULTS An asymptomatic 85-year-old woman with a history of bilateral penetrating keratoplasty presented for… read more here.
Keywords: graft rejection; corneal graft; graft; pembrolizumab treatment ... See more keywords
Angiogenic and Immune-Related Biomarkers and Outcomes Following Axitinib/Pembrolizumab Treatment in Patients with Advanced Renal Cell Carcinoma
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DOI: 10.1158/1078-0432.ccr-20-1408
Abstract: Purpose: Combined axitinib/pembrolizumab is approved for advanced renal cell carcinoma (aRCC). This exploratory analysis examined associations between angiogenic and immune-related biomarkers and outcomes following axitinib/pembrolizumab treatment. Patients and Methods: Prospectively defined retrospective correlative exploratory analyses… read more here.
Keywords: related biomarkers; treatment; pembrolizumab treatment; axitinib pembrolizumab ... See more keywords
PD-1-inhibitor pembrolizumab for treatment of progressive multifocal leukoencephalopathy
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic Advances in Neurological Disorders"
DOI: 10.1177/1756286421993684
Abstract: The reactivation of human JC polyoma virus (JCPyV) results in lytic infection of oligodendrocytes and neuronal cells. The corresponding clinical picture is called progressive multifocal leukoencephalopathy (PML) and results mostly from a disease-related or drug-induced… read more here.
Keywords: inhibitor pembrolizumab; treatment; progressive multifocal; multifocal leukoencephalopathy ... See more keywords
Pembrolizumab for the treatment of advanced esophageal cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Future oncology"
DOI: 10.2217/fon-2022-0108
Abstract: The prognosis of patients with advanced esophageal cancer (EC) remains poor and there are limited effective therapeutic agents for EC. Pembrolizumab monotherapy exerts clinically meaningful benefits for advanced esophageal squamous cell carcinoma patients with a… read more here.
Keywords: esophageal cancer; advanced esophageal; pembrolizumab treatment; patients advanced ... See more keywords
Circulating CD137+ T Cell Levels Are Correlated with Response to Pembrolizumab Treatment in Advanced Head and Neck Cancer Patients
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087114
Abstract: Pembrolizumab, an anti-PD-1 antibody, has been approved as first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma ((R/M) HNSCC). However, only a minority of patients benefit from immunotherapy, which highlights the need… read more here.
Keywords: head neck; cd137 cells; pembrolizumab treatment; circulating cd137 ... See more keywords
Use of Pembrolizumab for Treatment of Progressive Multifocal Leukoencephalopathy in People Living with HIV
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DOI: 10.3390/v14050970
Abstract: Progressive Multifocal Leukoencephalopathy (PML) is a demyelinating disease occurring in advanced HIV infection, caused by the reactivation of poliomavirus JC (JCV). The use of pembrolizumab for treatment is based on the inhibition of programmed cell… read more here.
Keywords: hiv; multifocal leukoencephalopathy; progressive multifocal; pembrolizumab treatment ... See more keywords