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Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.07.026
Abstract: POSTER DISCUSSION SESSION 1 AUGUST 18, 2018 — 08:00 e 09:15 PD.1.01 Health-Related Quality of Life with Pembrolizumab or Placebo + Pemetrexed + Platinum in Non-Squamous NSCLC: KEYNOTE-189 M. Garassino, D. Rodríguez-Abreu, S. Gadgeel, E.…
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Keywords:
placebo pemetrexed;
pembrolizumab;
placebo;
health ... See more keywords
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Published in 2020 at "Lung cancer"
DOI: 10.1016/j.lungcan.2020.07.024
Abstract: OBJECTIVES Apatinib showed efficacy in non-small cell lung cancer (NSCLC). We conducted this phase II clinical study to assess the efficacy and safety of apatinib in combination with pemetrexed-platinum chemotherapy in non-squamous NSCLC (Clinical Trial…
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Keywords:
chemotherapy;
non squamous;
combination pemetrexed;
lung cancer ... See more keywords
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Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-20-1306
Abstract: Purpose: Ganetespib, a highly potent, small-molecule Heatshock protein 90 inhibitor, has potential efficacy in malignant pleural mesothelioma (MPM) via activity on critical survival pathways and known synergies with antifolates and platinum chemotherapy. We conducted a…
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Keywords:
chemotherapy;
pleural mesothelioma;
ganetespib;
phase trial ... See more keywords
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Published in 2019 at "Clinical Trials"
DOI: 10.1158/1538-7445.am2019-ct043
Abstract: Background: KEYNOTE-189 is a randomized, placebo-controlled, Phase III study of pembro plus pemetrexed-platinum versus placebo plus pemetrexed-platinum among pts with metastatic nonsquamous NSCLC. At median follow-up of 10.5 months, pts in the pembro-combination arm had…
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Keywords:
nonsquamous nsclc;
plus pemetrexed;
pemetrexed platinum;
brain metastases ... See more keywords
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Published in 2022 at "OncoTargets and therapy"
DOI: 10.2147/ott.s332998
Abstract: Background Recent clinical trials illustrated that gefitinib plus pemetrexed/platinum regimen improves survival in advanced lung adenocarcinoma patients with EGFR mutation, while data on its efficacy and safety in a real clinical setting are limited. Thus,…
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Keywords:
lung adenocarcinoma;
pfs;
pemetrexed platinum;
group ... See more keywords