Cost-Utility Analysis of Rituximab vs Mycophenolate Mofetil for the Treatment of Pemphigus Vulgaris.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.2878
Abstract: Importance There is an increasing body of literature that supports the use of rituximab as a first-line steroid-sparing agent in pemphigus vulgaris. However, the cost of rituximab is substantial compared with conventional agents, and there… read more here.
Keywords: rituximab biosimilars; cost; pemphigus vulgaris; mycophenolate mofetil ... See more keywords
Autologous platelet-rich plasma and triamcinolone acetonide intralesional injection in the treatment of oral erosions of pemphigus vulgaris: a pilot study
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-018-1824-x
Abstract: Oral erosions of pemphigus vulgaris (PV) represent a therapeutic challenge. In this work we compared intralesional injection of steroids (ILS) and autologous platelet-rich plasma (PRP) treatment of oral erosions of PV. In this split–mouth randomized… read more here.
Keywords: pemphigus vulgaris; oral erosions; treatment oral; treatment ... See more keywords
Neonatal pemphigus vulgaris characterized by tensive blisters
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DOI: 10.1007/s12519-019-00292-w
Abstract: Neonatal pemphigus vulgaris (NPV) is a transient immunobullous disease, and its pathogenesis involves the passive transfer of maternal immunoglobulin G (IgG) antibodies through the placenta from a mother to the fetus [1]. Individuals aged 40–60… read more here.
Keywords: pemphigus vulgaris; vulgaris characterized; characterized tensive; tensive blisters ... See more keywords
Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.07.093
Abstract: SUMMARY Lineage analysis of autoreactive B cells can reveal the origins of autoimmunity. In the autoimmune disease pemphigus vulgaris (PV), desmoglein 3 (DSG3) and DSG1 autoantibodies are predominantly of the IgG4 subclass and less frequently… read more here.
Keywords: pemphigus vulgaris; disease pemphigus; iga; autoimmune disease ... See more keywords
Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.06.066
Abstract: SUMMARY Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering sores on skin and mucosal membranes, caused by autoantibodies primarily targeting the cellular adhesion protein, desmoglein-3 (Dsg3). To better understand how Dsg3-specific autoantibodies develop… read more here.
Keywords: pemphigus vulgaris; vulgaris autoimmune; disease; autoimmune disease ... See more keywords
Correlation between polymorphisms of the NR3C1 gene and glucocorticoid effectiveness in patients with pemphigus vulgaris
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DOI: 10.1038/s41598-017-12255-0
Abstract: AbstractsGlucocorticoid (GC) resistance is the major obscule in the treatment of pemphigus vulgaris (PV) for both patients and clinicans with unclear mechanism. A hypotheis for this resistance is the mutations or polymorphisms present in the… read more here.
Keywords: pemphigus vulgaris; resistance; correlation polymorphisms; effectiveness patients ... See more keywords
Efficacy and safety of biosimilar rituximab in the treatment of pemphigus vulgaris: a single center experience of 12 cases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2020.1729955
Abstract: Abstract Objective Rituximab, a chimeric monoclonal antibody that targets the CD-20 molecule on B-cells’ surface, has led to significant advances in the treatment of autoimmune pemphigus in recent decades. The aim of the study was… read more here.
Keywords: safety; rituximab; pemphigus vulgaris; treatment ... See more keywords
COVID-19 in pemphigus vulgaris patients with previous rituximab therapy: a tele-medicine experience
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2020.1789041
Abstract: Nowadays, rituximab, an anti-CD20 monoclonal antibody, has revolutionized the treatment of moderate to severe pemphigus from both safety and efficacy perspectives. We aimed to perform a tele-dermatology study to evaluate the development of COVID-19 or… read more here.
Keywords: medicine; pemphigus vulgaris; patients received; vulgaris patients ... See more keywords
Current status and prospects for the diagnosis of pemphigus vulgaris
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2021.1945925
Abstract: ABSTRACT Introduction: Pemphigus vulgaris (PV) is an intraepidermal autoimmune bullous disease (AIBD) characterized by autoantibodies against desmosomal adhesion proteins, most commonly desmoglein (Dsg)3, leading to the suprabasal cleft formation and acantholysis. Areas covered: Direct immunofluorescence… read more here.
Keywords: pemphigus vulgaris; immunofluorescence; current status; diagnosis pemphigus ... See more keywords
Immunological markers as predictors of developing steroid-induced diabetes mellitus in pemphigus vulgaris patients
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000010463
Abstract: Abstract The aim of this study was to evaluate the clinical importance of autoantibodies in pemphigus vulgaris patients who developed steroid-induced diabetes mellitus (SID) because of the glucocorticoid therapy of pemphigus. A total of 137… read more here.
Keywords: pemphigus vulgaris; steroid induced; vulgaris patients; induced diabetes ... See more keywords
Selective Plasma Exchange for the Removal of Pemphigus Autoantibodies, Fibrinogen, and Factor XIII in Pemphigus Vulgaris
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DOI: 10.1111/1744-9987.12555
Abstract: Pemphigus vulgaris is a serious autoimmune skin disorder associated with desmoglein 1 and 3. Selective plasma exchange (SePE) for pemphigus vulgaris remains unknown. We investigated the removal characteristics of pemphigus autoantibodies, immunoglobulins, and fibrinogen in… read more here.
Keywords: pemphigus vulgaris; factor xiii; selective plasma; pemphigus autoantibodies ... See more keywords