Berberine stimulates lysosomal AMPK independent of PEN2 and maintains cellular AMPK activity through inhibiting the dephosphorylation regulator UHRF1
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DOI: 10.3389/fphar.2023.1148611
Abstract: Aim: AMPK is the key regulatory kinase mediating the effect of berberine (BBR) and metformin on metabolic improvement. The present study investigated the mechanism of BBR on AMPK activation at low doses, which was different… read more here.
Keywords: pen2; bbr; lysosomal ampk; ampk activity ... See more keywords