Drug "Clicking" on Cell-Penetrating Fluorescent Nanoparticles for In Cellulo Chemical Proteomics.
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DOI: 10.1021/acs.bioconjchem.8b00481
Abstract: Chemical proteomics approaches are widely used to identify molecular targets of existing or novel drugs. This manuscript describes the development of a straightforward approach to conjugate azide-labeled drugs via click chemistry to alkyne-tagged cell-penetrating fluorescent… read more here.
Keywords: fluorescent nanoparticles; penetrating fluorescent; chemistry; chemical proteomics ... See more keywords