Stabilizing Effects of Bacterial Biofilms: EPS Penetration and Redistribution of Bed Stability Down the Sediment Profile
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Geophysical Research"
DOI: 10.1002/2017jg004050
Abstract: Biofilms, consisting of microorganisms and their secreted extracellular polymeric substances (EPS), serve as “ecosystem engineers” stabilizing sedimentary environments. Natural sediment bed provides an excellent substratum for biofilm growth. The porous structure and rich nutrients allow… read more here.
Keywords: bacterial biofilms; penetration; stabilizing effects; sediment ... See more keywords
A Fibrinogen‐Mimicking, Activated‐Platelet‐Sensitive Nanocoacervate Enhances Thrombus Targeting and Penetration of Tissue Plasminogen Activator for Effective Thrombolytic Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201265
Abstract: The development of a fibrinolytic system with long circulation time, high thrombus targeting, efficient thrombus penetration, effective thrombolysis, and minimal hemorrhagic risk remains a major challenge. Herein, inspired by fibrinogen binding to activated platelets in… read more here.
Keywords: rgd chi; penetration; tpa; chi tpa ... See more keywords
Virion-Like Membrane-Breaking Nanoparticles with Tumor-Activated Cell-and-Tissue Dual-Penetration Conquer Impermeable Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201707240
Abstract: Poor drug penetration into tumor cells and tissues is a worldwide difficulty in cancer therapy. A strategy is developed for virion-like membrane-breaking nanoparticles (MBNs) to smoothly accomplish tumor-activated cell-and-tissue dual-penetration for surmounting impermeable drug-resistant cancer.… read more here.
Keywords: penetration; membrane breaking; virion like; tissue ... See more keywords
A Size-Changeable Collagenase-Modified Nanoscavenger for Increasing Penetration and Retention of Nanomedicine in Deep Tumor Tissue.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.201906745
Abstract: The complex tumor microenvironment constitutes a variety of barriers to prevent nanoparticles (NPs) delivery and results in extremely low accumulation of nanomedicines in solid tumors. Here, a newly developed size-changeable collagenase-modified polymer micelle is employed… read more here.
Keywords: tumor tissue; penetration; collagenase; retention ... See more keywords
A Dendritic Polymer‐Based Nanosystem Mediates Drug Penetration and Irreversible Endoplasmic Reticulum Stresses in Tumor via Neighboring Effect
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202201200
Abstract: Nanoparticles (NPs)‐based cancer therapeutics are generally impeded by poor drug penetration into solid tumors due to their dense tumor extracellular matrix (ECM). Herein, pH/redox‐responsive dendritic polymer‐based NPs are developed to amplify the neighboring effect for… read more here.
Keywords: effect; penetration; dendritic polymer; neighboring effect ... See more keywords
Sequentially Triggered Nanoparticles with Tumor Penetration and Intelligent Drug Release for Pancreatic Cancer Therapy
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201701070
Abstract: Abstract Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive malignancy with a five year survival rate of read more here.
Keywords: pdac; penetration; drug; cpp ... See more keywords
Enhancing Penetration Ability of Semiconducting Polymer Nanoparticles for Sonodynamic Therapy of Large Solid Tumor
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104125
Abstract: Sonodynamic therapy (SDT) holds growing promise in deep‐seated or large solid tumor treatment owing to its high tissue penetration depth ability; however, its therapeutic efficacy is often compromised due to the hypopermeable and hypoxic characteristics… read more here.
Keywords: tumor; penetration; solid tumor; large solid ... See more keywords
Investigation of Sequence‐Penetration Relationships of Antisense Oligonucleotides
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202300009
Abstract: A major limitation for the development of more effective oligonucleotide therapeutics has been a lack of understanding of their penetration into the cytosol. While prior work has shown how backbone modifications affect cytosolic penetration, it… read more here.
Keywords: investigation sequence; cytosolic penetration; penetration; sequence ... See more keywords
Investigation of the effect of different chelation solutions on penetration of resin‐based and bioceramic sealers with a novel method
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.23717
Abstract: This study aimed to investigate the effects of different chelation solutions on the penetration of resin‐based and bioceramic root canal sealers into dentinal tubules using a device that assembles conventional microplate detection with automated digital… read more here.
Keywords: chelation solutions; microscopy; penetration; solutions penetration ... See more keywords
Evaluation of interfacial adaptation and penetration of bioceramic-based sealers in oval root canals: A confocal laser scanning microscope study.
Sign Up to like & getrecommendations! Published in 2023 at "Microscopy research and technique"
DOI: 10.1002/jemt.24323
Abstract: To assess the interfacial adaptation and penetration depth of three different bioceramic-based sealers (CeraSeal, EndoSeal MTA, Nishika Canal Sealer BG) compared to an epoxy resin-based sealer (AH Plus) in oval root canals. Fourty extracted single-rooted… read more here.
Keywords: adaptation penetration; endoseal mta; nishika canal; penetration ... See more keywords
Evaluating the effect of different irrigation activation techniques on the dentin tubules penetration of two different root canal sealers by laser scanning confocal microscopy.
Sign Up to like & getrecommendations! Published in 2023 at "Microscopy research and technique"
DOI: 10.1002/jemt.24339
Abstract: PURPOSE The aim of this study is to evaluate the effect of different irrigation activation techniques on the dentin tubules penetration of two different sealers by confocal laser scanning microscope (CLSM). METHODS A hundred premolar… read more here.
Keywords: irrigation; activation techniques; penetration; tubule penetration ... See more keywords