Sterols and pentacyclic triterpenoids from nettle root: content and composition as affected by pressurized liquid extraction.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12373
Abstract: BACKGROUND Nettle is a medicinal plant rich in bioactive molecules. The composition of nettle leaves and stems has been extensively studied, whereas the root has been insufficiently investigated. Therefore, the present study aimed to optimize… read more here.
Keywords: nettle root; root; pressurized liquid; liquid extraction ... See more keywords
Recent progress in the antiviral activity and mechanism study of pentacyclic triterpenoids and their derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Medicinal Research Reviews"
DOI: 10.1002/med.21484
Abstract: Viral infections cause many serious human diseases with high mortality rates. New drug‐resistant strains are continually emerging due to the high viral mutation rate, which makes it necessary to develop new antiviral agents. Compounds of… read more here.
Keywords: pentacyclic triterpenoids; activity mechanism; antiviral activity; progress antiviral ... See more keywords
Quorum quenching activity of pentacyclic triterpenoids leads to inhibition of biofilm formation by Acinetobacter baumannii
Sign Up to like & getrecommendations! Published in 2020 at "Biofouling"
DOI: 10.1080/08927014.2020.1831480
Abstract: Abstract The quorum quenching (QQ) potential of three pentacyclic triterpenoids, glycyrrhetinic acid (GRA), ursolic acid (UA) and betulinic acid (BA), representing distinct groups of compounds, was evaluated. Violacein production by Chromobacterium violaceum and pyocyanin production… read more here.
Keywords: pentacyclic triterpenoids; biofilm formation; acinetobacter baumannii; quorum quenching ... See more keywords
Pentacyclic triterpenoids from the stem of Grewia bracteata Roth demonstrate promising inhibition on tumour cells.
Sign Up to like & getrecommendations! Published in 2023 at "Natural product research"
DOI: 10.1080/14786419.2023.2180504
Abstract: Grewia bracteata Roth stem was investigated for its anticancer potential for the first time. Initially, polarity-guided extracts from three solvents were screened on HeLa, HCT- 116 and MCF-7 tumours cells. The results revealed that ethyl… read more here.
Keywords: pentacyclic triterpenoids; grewia bracteata; stem grewia; bracteata roth ... See more keywords
Pentacyclic triterpenoids as antibiofilm agents against methicillin-resistant and biofilm-forming Staphylococcus aureus (MRSA).
Sign Up to like & getrecommendations! Published in 2021 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201022666210806092643
Abstract: BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) has been constantly evolving and developing resistance against conventional antibiotics. One of the key features of MRSA that enables it to develop resistance to antibiotics and host immune system is… read more here.
Keywords: staphylococcus aureus; pentacyclic triterpenoids; aureus mrsa; methicillin resistant ... See more keywords
Pentacyclic Triterpenoids-Based Ionic Compounds: Synthesis, Study of Structure–Antitumor Activity Relationship, Effects on Mitochondria and Activation of Signaling Pathways of Proliferation, Genome Reparation and Early Apoptosis
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15030756
Abstract: Simple Summary The search for new, effective and low-toxicity anticancer drugs is one of the most important tasks of modern medicinal chemistry. Pentacyclic triterpenoids constitute an important class of biologically active compounds with a wide… read more here.
Keywords: antitumor activity; ionic compounds; pentacyclic triterpenoids; structure ... See more keywords
Pentacyclic Triterpenoids from Sabia discolor Dunn and Their α-Glycosidase Inhibitory Activities
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27072161
Abstract: Four new pentacyclic triterpenoids named Sabiadiscolor A–D (1 and 7–9) together with eleven known ones were isolated by repeated column chromatography. Their structures were identified and characterized by NMR and MS spectral data as 6… read more here.
Keywords: sabia discolor; pentacyclic triterpenoids; discolor dunn; glycosidase inhibitory ... See more keywords
Determination of Pentacyclic Triterpenoids in Plant Biomass by Porous Graphitic Carbon Liquid Chromatography—Tandem Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28093945
Abstract: Pentacyclic triterpenoids (PCTs), which possess a number of bioactive properties, are considered one of the most important classes of secondary plant metabolites. Their chromatographic determination in plant biomass is complicated by the need to separate… read more here.
Keywords: chromatography tandem; plant biomass; liquid chromatography; pentacyclic triterpenoids ... See more keywords
Supercritical Fluid Chromatography—Tandem Mass Spectrometry for Rapid Quantification of Pentacyclic Triterpenoids in Plant Extracts
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15050629
Abstract: Pentacyclic triterpenoids (PCTs) are a widely distributed class of plant secondary metabolites. These compounds have high bioactive properties, primarily antitumor and antioxidant activity. In this study, a method was developed for the quantitative analysis of… read more here.
Keywords: mass spectrometry; supercritical fluid; pentacyclic triterpenoids; plant ... See more keywords