Articles with "pentanoate suppresses" as a keyword



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The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

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Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-08711-2

Abstract: Short-chain fatty acids (SCFAs) have immunomodulatory effects, but the underlying mechanisms are not well understood. Here we show that pentanoate, a physiologically abundant SCFA, is a potent regulator of immunometabolism. Pentanoate induces IL-10 production in… read more here.

Keywords: fatty acid; short chain; pentanoate; pentanoate suppresses ... See more keywords