Comparative study of dezocine, pentazocine and tapentadol on antinociception and physical dependence.
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DOI: 10.1016/j.lfs.2021.119996
Abstract: AIMS Dezocine and pentazocine, widely prescribed in China for postoperative pain, were initially considered as mixed agonist/antagonist targeting μ-opioid receptors (MORs) and κ-opioid receptors (KORs). However, dezocine has been revealed to alleviate chronic neuropathic pain… read more here.
Keywords: pentazocine; dezocine pentazocine; tapentadol; antinociception ... See more keywords
Linezolid in combination with pentazocine causes serotonin syndrome: A case report
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DOI: 10.1097/md.0000000000043517
Abstract: Rationale: Serotonin syndrome (SS) is a potentially life-threatening condition characterized by autonomic and muscular hyperactivity resulting from the use of serotonergic drugs that bind to peripheral or central postsynaptic serotonin receptors. This syndrome can be… read more here.
Keywords: linezolid pentazocine; report; serotonin syndrome; linezolid combination ... See more keywords
Negative modulation of spinal κ-opioid receptor-mediated antinociception by the µ-opioid receptor at selective doses of (−)-pentazocine
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DOI: 10.1097/wnr.0000000000001043
Abstract: The mixed-action &kgr;-opioid receptor (KOR) agonist, pentazocine, binds to both KOR and the µ-opioid receptor (MOR). Racemic (±)-pentazocine and (−)-pentazocine, each administered systemically, have been shown to produce antinociception in various animal models. In contrast,… read more here.
Keywords: pentazocine; antinociception; opioid receptor; mor ... See more keywords